| Purpose:To investigate the distribution of physique types of central serous chorioretinopathy(CSC)in traditional Chinese medicine(TCM),explore the distribution rule of TCM physique characteristics,and observe the clinical effect of different physique CSC patients after intervention of Chinese medicine,analyze the relationship between TCM physique and clinical efficacy,provide effective methods and research ideas for the prevention and treatment of CSC in the future.Methods:A questionnaire survey of TCM physique was conducted on 100 patients who met the diagnostic criteria of CSC in the ophthalmological outpatient department of Jiangsu Provincial traditional Chinese Medicine Hospital.According to the classification and criteria of TCM constitution,they were divided into nine basic types:normal-constitution,qi deficiency constitution,yin deficiency constitution,yang deficiency constitution,phlegm-dampness constitution,damp-heat constitution,blood-stasis constitution,qi-stagnation constitution,and special constitution.All the patients were treated with the tutor's experience prescription.The height of highest point of subretinal fluidd(HPSF)was measured by using visual acuity,conscious symptoms and the highest elevation of the subretinal fluid protuberance to the height of the retinal pigment epithelium as the observed indicator,to analyze the correlation between TCM physique type and clinical curative effect.Results:(?A total of 100 CSC patients were investigated in this study,including 53 males,(40.57±10.13)years old,and course of disease for(6.4±4.5)days;47 females,(48.00±8.52)years old,and course of disease for(6.0±2.9)days.The age difference between male and female was statistically significant(P<0.001).The onset age of male was earlier than that of female.?The frequency of various types of TCM Constitution in CSC patients was in the following order:phlegm dampness phlegm-dampness constitution(36%)>qi-stagnation constitution(25%)>normal-constitution(20%)>qi deficiency constitution(8%)>(5%)yang deficiency constitution>yin deficiency constitution(2%)=(2%)damp-heat constitution=(2%)blood-stasis constitution>special constitution(0%)?There was no significant statistical difference(P>0.05)between gender and TCM constitution type in CSC patients,but age was closely related to TCM physique type(P<0.05).?There was no significant difference in the distribution of visual acuity between different TCM physique types of CSC patients and 1 month and 3 months after treatment(P>0.05).But in the single constitution,there was significant difference in the distribution of visual acuity in CSC patients with phlegm damp,qi stagnation and calmness(P<0.01).?There was no significant difference in the distribution of subretinal fluid absorption between different TCM physique types and subretinal fluid absorption in 1 and 3 months after operation in patients with CSC(P>0.05).But for single physical constitution,there was significant difference in the distribution of liquid phlegm in patients with CSC(P<0.01)1 month after operation;for CSC patients with phlegm-dampness constitution(P=0.013),qi-stagnation constitution(P=0.026),and normal-constitution(P<0.001),absorption distribution of liquid 3 months after operation were statistically significantly different..?CSC patients with different TCM type of constitution 1 month after treatment,their symptom distribution showed significant differences(P<0.05),for patients of phlegm-dampness constitution with CSC,the distribution had statistically significant difference(P=0.005);3 months after the treatment,the distribution of various physical symptoms showed no significant difference(P>0.05),and for CSC patients with phlegm-dampness constitution(P=0.005),qi-stagnation constitution(P=0.028)there was significant difference in symptoms of CSC distribution.Conclusion:This research indicates that CSC has certain correlation with TCM physique,and it is more common in phlegm-dampness constitution,qi-stagnation constitution and normal-constitution.The correlations between TCM physique type and sex and age of CSC exist objectively.With TCM intervention treatment,CSC patients with phlegm-dampness constitution,qi-stagnation constitution and normal-constitution have better clinical efficacy. |
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