Study On Clinical Characteristics And TCM Syndromes Of Urinary Sepsis

ObjectiveTo observe the changes of coagulation parameters such as WBC,NEU,PCT and PLT,PT,APTT and FIB in the pathogenesis of urinary sepsis,and to provide the diagnostic basis for the early diagnosis of urinary sepsis.At the same time to explore the characteristics of urinary sepsis TCM syndrome,for the traditional Chinese medicine to provide an objective basis for syndrome differentiation.MethodsThrough the retrospective study method,collected from September 2014 to May 2017,Guangzhou University of Traditional Chinese Medicine,Department of Urology and Severe Medicine 41 cases of urinary sepsis discharged cases as the observation group,select 96 cases of common urinary tract infection Cases as a control group.The data of the discharged cases in the observation group and the control group were sorted and summarized.The APBCE II score,urine combination,clean urine culture,renal pelvic culture,blood culture and WBC,NEU,PLT,PT,APTT were recorded in the observation group.,FIB,PCT and other changes in information.The differences of WBC,NEU,PLT,PT,APTT and FIB between the observation group and the control group were compared between the observation group and the control group at 6h,12 h,24h,3d,7d and so on.,Summed up its changing trend.At the same time,according to the collection of observation group of four medical information,according to diagnostic criteria for diagnosis.And the TCM syndromes were reanalyzed to summarize their main syndromes and symptoms.The collected case information is input into the database,and the SPSS22 software is used for statistical analysis.Results1.From the urinary sepsis and general urinary tract infection in patients with the incidence of analysis,women are the main population,of which the control group and observation group were 41-70 age group incidence of more.Among the 41 patients with urinary sepsis,19(46.34%)were admitted to hospital for acute urinary tract obstruction and 3 patients(7.32%)with acute pyelonephritis were enrolled in the study.19 cases(46.34%),combined with upper urinary tract stones in 39 cases(95.12%).28 cases of urine culture positive,total urine culture positive rate of 68.29%,10 cases of peripheral blood culture positive,the total positive rate of 24.39%;the main pathogen is Escherichia coli,accounting for 47.06%,followed by Candida glabrata,accounting for 14.71%,Staphylococcus aureus,Staphylococcus aureus,Klebsiella pneumoniae each accounted for 5.89%,Staphylococcus aureus,Staphylococcus aureus,Staphylococcus aureus,Candida tropicalis,Mora bacteria,Enterococcus faecalis,Pseudomonas aeruginosa and other 2.94%.2.There were significant differences in PCT,WBC,NEU,PLT,APTT,PT,FIB between the control group and the observation group(P <0.05).There were significant differences between the two groups(P <0.05)at 12 hours,24 hours,3 days and 7 days after treatment,such as PCT,WBC,NEU,PLT,APTT and PT.The overall trend of WBC,NEU,PCT,APTT and PT changes gradually with the progress of inflammation.The peak of WBC,NEU,APTT and PT reached the peak at 24 hours.The peak of PCT reached the peak at 12 hours,The control gradually declined.With the progression of inflammation,PCT peaked at 12 hours and PLT decreased gradually and dropped to the lowest level at 12 hours after onset.When infection was controlled,PLT increased gradually.3.Will be included in the standard of patients with a total of 41 cases of Chinese medicine four diagnostic information evaluation,the symptoms of the cases of frequency and probability statistics,the results show fever,chills,pale,apathetic and other 30 symptoms in more than 20%.According to the actual situation of the syndrome,the symptoms of the symptoms of the questionnaire in accordance with the standard diagnostic criteria for syndromes classification,obtained hot flames,wet resistance,blood stasis,stone resistance,qi deficiency,blood deficiency,yang deficiency,The highest incidence rate of stone resistance was 92.683%,the occurrence rateof hot flashes was 73.171%,the occurrence rate of wet resistance was 58.037%,the incidence rate of blood stasis was 56.098%,the occurrence rate of Qi deficiency was 7.317% The incidence of evidence was 26.829%,the incidence of yin deficiency was 19.512%,and the incidence of yang deficiency was 7.317%.ConclusionUrine-type sepsis early onset of inflammation and coagulation-related indicators that have changed.Among them,such as WBC,NEU,PCT,PLT and other indicators of early onset there is a significant change,can be used as early judgments based on the disease.And APTT,PT,FIB and other indicators of change is not large,may be the early diagnosis of urinary sepsis is not high value.Urine-type sepsis early onset of the main manifestations of Zheng Sheng evil,to the main performance of stone resistance,which is the main evidence for the type of evidence.