Clinical Study About The Efficacy Of Shugansijun Decoction To Functional Dyspepsia(Weipi,Disharmony Of Liver And Stomach)

Objective: This study aims to evaluate the clinical efficacy and safety of Shugansijun decoction in the treatment of functional dyspepsia/Weipi(Disharmony of liver and stomach)in patients with functional dyspepsia/Weipi.Further explore the therapeutic effects of Chinese medicine on functional dyspepsia/Weipi and provide new methods for the treatment of functional dyspepsia/Weipi(Disharmony of liver and stomach)in traditional Chinese medicine.Methods: Eighty-two patients with functional dyspepsia/Weipi who met the inclusion criteria were randomly divided into treatment group and control group with41 cases each.The treatment group was given oral Shugansijun decoction(Bupleurum 10 g,Cyperus 10 g,Kawashima 10 g,North Adenophora 30 g,Fried Atractylodes 15 g,Fried clams 15 g,White Pelican 15 g,Poria 30 g,Pueraria 30 g,Fried yellow quail 15 g,Licorice 10g-drug sources were all selected from the traditional Chinese medicines provided by the Chinese Medicine Hospital of Yunnan Province Traditional Chinese Medicine Hospital.The Chinese medicine hospital of Yunnan Province Traditional Chinese Medicine Hospital decocted the medicine on behalf of the traditional Chinese medicine),1 day,3 times / day,each time 150ml(one package),warm clothes for half an hour after meals.The control group was treated with orally administered Mosapride citrate dispersible tablets(commercial name:Xinluona,manufactured by Chengdu Kanghong Pharmaceutical Group Co.,Ltd.,batch number: # raw H20031110),each time 5mg,3 times a day,half an hourbefore meals Hours orally.The treatment is also 2 weeks.The clinical efficacy and safety indicators were observed and recorded in both groups after 2 weeks of treatment.Results: Before treatment,there was no statistically significant difference in the age,sex,and course of disease distribution and pre-treatment HAMA and HAMD scores(P>0.05),and they were comparable.1.After treatment,the total effective rate of the treatment group was 92.5%,which was significantly higher than the 77.5% of the total effective rate in the control group(P<0.05).2.Comparison of changes in individual symptom scores before and after treatment: The treatment group was significantly better than the control group in improving both symptoms of fullness of stress and upset irritability(P<0.01).It improved the pain of the stomach and was not comfortable.There was no significant difference between the two groups in improving nausea and belching symptoms(P>0.05).3.The treatment group was effective in relieving the anxiety and depressive symptoms of patients(P<0.01),and was superior to the control group(P<0.01).4.During the trial period,no abnormal changes were found in the urine analysis,stool routine,occult blood,and electrocardiogram examination.There were no obvious adverse reactions and side effects;differences in blood routine,liver function,and renal function between the two groups were not significant.No statistical significance(P>0.05).Conclusion: Shugansijun decoction has the effect of improving functional dyspepsia/Weipi(Disharmony of liver and stomach).Compared with the control group,the curative effect was better in improving TCM syndromes,anxiety,and depression;it was better than the control group in improving the symptoms of fullness of stress,upset irritability,stomach pain,uncomfortable phlegm,good rest,and stool..And its safety is good,it can be used as a treatment of functional dyspepsia / Weipi(Disharmony of liver and stomach)choice and reference.