Rule Of Chinese Medicine For Multiple Sclerosis Based Onliterature Data Mining

Purpose: This topic through collecting Chinese journal full-text database and Chinese science and technology periodical database,ten thousand party full-text database of Chinese medicine literature and combining traditional Chinese and western medicine treatment of multiple sclerosis,applying data mining technology,dig out the task the clinical rule of multiple sclerosis.Method: Through to the electronic collection of self-built database retrieval library up to October 2016 before about the document of traditional Chinese medicine and combining traditional Chinese and western medicine treatment of multiple sclerosis,using Microsoft Office Excel 2007 to establish the original database,according to the inclusion criteria and exclusion criteria,select input original database,conform to the requirements of the literature and the literature preprocessing,Through the method of frequency analysis for high frequency drugs and drug classes,adopts the method of system cluster analysis for drug that is close to the composition and the clustering,summed up the medication rule of multiple sclerosis.Result: 128 articles were collected,including 194 prescriptions,264 taste traditional Chinese medicine,through the frequency statistics show:Total frequency of 2578 times,use frequency is highest is the root of remembranous milk vetch,a total of 99 times.Drug use frequency is less than 10 times for a total of 195,among them,the small frequency is equal to three times of traditional Chinese medicine with a total of 135.The use of frequency with six big drugs equals 60 times flavour,astragalus,licorice,Chinese angelica,poria cocos,radix paeoniae alba,atractylodes.Use frequency is equal to 50 times four flavor of traditional Chinese medicine: rehmannia glutinosa,twotooth achyranthes root,pinellia,dogwood.Using large frequency is equal to 40 times of traditional Chinese medicine has eight: is,in turn,batryticated silkworm,codonopsis,rhizoma ligustici wallichii,coix seed,epimedium herb,radix paeoniae rubra,radix rehmanniae(40)and salvia miltiorrhiza(40).Drug use large frequency is equal to 30 times seven,medlar(39),scorpion(39),dodder(39),dried tangerine or orange peel,alisma,fructus ligustri lucidi,radix puerariae.Large frequency is equal to 20 times the drug 16,in turn,is lumbricus(28),stone calamus(28),safflower,radix bupleuri,cassia twig(24),yam(24),nut(24)and radix polygoni multiflori cane(23),jujube(23),medicinal indianmulberry root,eucommia bark(21),cortex moutan(21),cortex phellodendri(21),gastrodia elata(21),tortoise shell,bravery nanxing(21).Rounding out the top 10 kinds of drugs for: astragalus,licorice,Chinese angelica,poria cocos,radix paeoniae alba,atractylodes,rehmannia glutinosa,twotooth achyranthes root,pinellia,dogwood.Big frequency of medicine is equal to 10 times of traditional Chinese medicine with a total of 69,take medicine frequency was 77.92%.In the commonly used drugs,involved the nineteenth class of drugs,mainly for virtual medicine,promoting blood circulation to remove blood stasis drugs,clear heat,flat extinguish wind liver medicine,nourish,phlegm cough antiasthmatic drugs,the water moisture penetration,accounts for over 70% of the total drug use frequency,as the mainstay of treatment for multiple sclerosis,followed by(medicine,astringent medicine,qi,etc,in the treatment of multiple sclerosis sex also play an important role.Use frequency is equal to 20 times of traditional Chinese medicine with a total of 40,cluster analysis on the system,it is concluded that four clustering and 17 on,reflected the diversity of pathogenesis and treatment of multiple sclerosis.Conclusion: Through research,according to the results of promoting blood circulation to remove blood stasis,liver extinguish wind,dampness,invigorating spleen wet,nourishing liver and kidney is the modern subject such as commonly used therapeutic principles for the treatment of multiple sclerosis.From the perspective of the medication the etiology and pathogenesis of multiple sclerosis is complexity.Through the data mining method,nourishing liver and kidney,promoting blood circulation to remove blood stasis,extinguish wind antispasmodic and reconcile camp guard for the commonly used drugs and drugs for multiple sclerosis,provide certain theoretical guidance for clinical doctors to treat the disease.