Investigation And Analysis Of Proprietary Chinese Medicine Injection To Treat Ischemic Cerebral Apoplexy

Ischemic cerebral apoplexy,cerebral infarction accounted for 85% of the total stroke,clinical manifestations is hemiplegia,eye and mouth oblique,and bad language.Chinese stroke incidence is the highest in the world.National third cause of death review sampling survey data show that the current stroke has become China's cause of death and disability in patients with the first factor,in 2013,the death toll caused by cerebral apoplexy is as high as 1.7million,.According to data,the recurrence rate was high once again.Although medical technology for the treatment of cerebrovascular disease is constantly improving,cerebral infarction,the recurrence rate and fatality rate of deformity seriously still no great improvement.On the basis of neurology branch of Chinese medical association,the Chinese medical association branch of neurology cardiovascular epidemiology group written guidance of diagnosis and treatment of acute ischemic stroke in China 2014,which referred to western medicine treatment is to improve cerebral blood circulation and nerve protection as the key point.Chinese medicines and proprietary Chinese medicine injection in treatment of acute ischemic need more high quality clinical randomized controlled trials confirm,.Therefore,the treatment of ischemic stroke(cerebral infarction)in the application of proprietary Chinese medicine injection were investigated,to understand the situation and the occurrence of adverse reactions for use,can provide reference for scientific research and clinical treatment.Objective:In order to investigate and analysis of the proprietary of Chinese medicine injection in the treatment of ischemic stroke,the research of the non randomized controlled randomized controlled literature to the literature,sample size,dose,treatment,solvent,drug combination,adverse reactions,and conclusion was provided,and the reference for related research work and clinical application in the future was also studied.Methods:Literature comes from Chinese full-text database(CNKI)before 2016,ten thousand published in the journal full-text database,including thurber paper,meetings,papers,proprietary Chinese medicine injection for clinical interventions,case and comparative literature.Using the method of literature investigation,the number of published literature and the research content with Noteexpress literature retrieval and retrieval model for the title = "injection/agent" and title = "ischemic stroke" or "cerebral infarction" or "cerebral infarction" or "cerebral embolism" or "cerebral thrombosis" or "ischemic stroke" or "ischemic cerebrovascular disease" or "ischemic stroke and title =" clinical " or " case " or " controlled were downloaded,with statistical analysis and auxiliary Excel2007.Results:2033 references were founded in Hownet,and the repeated 1391 references were removed,642 references were the remained.2133 references were founded in Wan Fangjian literature,and the repeated 2114 references were removed.968 papers were removed from two addition of library literature,1788 were remained.The proprietary of Chinese medicine injection including a total of 68 species,according to the theory of traditional Chinese medicine,more with promoting blood circulation were studied,including Dan hong injection,ShuXueTong injection,lamps injection,lamps asarum injection,GeGen Su injection,MaiLuoNing injection,Ku DieZi injection.Besides,XingNaoJing injection,invigorate the circulation of the brain,CiWuJia injection benefit the bones,liver and kidney,Shen Mai injection increased the body upright and avoided the loss of the essence,at the same time maintaining the body fluid,ShenFu injection increased the body upright and avoided the loss of the essence,TianMaSu injection removed cold wind,make the JingLuo patency,GuaLouPi injection make the body unstructed and make chest smooth,etc.Conclusion:1.Such documents referred to in the types of clinical studies mostly random controlled study,clinical observation class is less.2.Such injection used in acute stage,recovery and sequelae period is less,either a period,dialectical drugs are less.3.Promoting blood circulation to remove blood stasis type medicine most,astragalus membranaceus fill gas most classes of drug combination.4.Little about normal dose and the clinical randomized controlled trial study,the use should be increased in the future research in this field.5.Usage is super treatment,medication should be interval for a period of time as far as possible go,as far as possible and check of the disease.6.There is not according to the instruction manual use of solvent.7.Appropriate interval time in combination is not recommended interval sequential dosing after infusion,in the case of security can dialectical union different efficacy of drugs.8.Record adverse reactions is not clear.