Research On The Medical Academic Thought And Compatibility Principles Of Drugs In "Xiaoeryaozhengzhijue" Of Qian Yi

Objective: Based on reading the original fully,to study on medical academic thought of Qian Yi and "xiaoeryaozhengzhijue" contained in prescription information comprehensively,careful arrangement,and auxiliary calculation and statistics,using modern information technology,full range,multi-level,in order to obtain some important rules in "xiaoeryaozhengzhijue " of Qian Yi prescriptions,accurately grasp the treatment experience of Qian Yi,for the transmission of medical academic thought,promote local application value to provide more effective way.Methods:1 Selecting Shanghai press of science and technology of the first edition in December 1958 "xiaoeryaozhengzhijue" as the research foundation,the version to Zhou Fu Ke ben to dibon,by Zhang Shanlei positive note.2 According to the "xiaoeryaozhengzhijue" in medical explanation,TCM treatment experience,compatibility principles of drugs and so on,through the collation,summary and analysis,to explore the medical academic thought of Qian Yi.3 Based on reading of the original work fully,the original function of the prescription,recorded in attending and compatibility of drugs,dosage and other information to conduct a comprehensive,detailed arrangement,and create a text file.First of all,for the effect of the original prescription and attending to sort and archived.Secondly,collation and archiving of the original prescription drug dosage in.Third,to working on the monarch drug in the prescription of.4 Putting the information getting from "xiaoeryaozhengzhijue" prescription,to the computer through the Word,Excel and Foxtable 2016 software all input,to establish a "Qian Yi " xiaoeryaozhengzhijue " prescription information database".5 Through the computer to "xiaoeryaozhengzhijue" recorded the prescription of statistical information and analysis.Firstly,according to the prescription effect and indications for statistics and analysis.Secondly,the statistics and analysis of the drug use frequency and dose.Thirdly,statistics and analysis according to the compatibility of drugs.Results:1 Qian Yi’s "xiaoeryaozhengzhijue" recorded 119 formula,uniform distribution in under load;oral prescription 111,topical prescription 8.All prescriptions involving a total of 189 herbs,among them,using the most is "heat-clearing medicine" 34 taste,then followed "asthma and eliminating phlegm" 12 taste,"liver pacifying wind subduing medicine" 11 taste,"releasing medicine" 10 taste,"astringent medicine" 10 taste.Composition of prescription drugs is the most "Qianghuo cream",23 herbs;herbs at least is the "Xiexin decoction","Antiperspirant powder","Firework cream","Baixiang pill","Niuli cream","Huisheng powder","Polygonum cuspidatum powder","Rhinoceros born mill juice",were taken orally,and taken topically "Arisaema powder",each have 1 medicine.2 "Xiaoeryaozhengzhijue" recorded in function of the prescription and indications:form the 119 prescriptions,the most use function is "Heat-clearing" 76 songs,then followed "Expectorant" 40 songs,"Treat wind" 31 songs,"Liqi" 21 songs,"Eliminate Stagnation" 18 songs.About the indications,119 prescriptions of "heat syndrome" 63 songs,then followed "phlegm syndrome" 31 songs,"spleen and stomach disease syndrome" 28 songs,"heart disease syndrome" 24 songs,"wind syndrome" 21 songs.The results show,Qian Yi pay attention to the significance of clearing away heat to treat diseases.3 "Xiaoeryaozhengzhijue" China agent involved in frequency of use and dosage of drugs:119 prescriptions involving 189 herbs,used a total of 609 times,the most frequently used,as "musk",there are 24 prescriptions,followed by "cinnabar" 20 prescriptions,"coptis" 19 prescriptions,"prepared Radix Glycyrrhizae" 18 prescriptions,"calomel" 16 prescriptions.The top five drugs in frequency of use:musk can enlighten,cinnabar can calm the nerves,coptiscan clear heat,prepared Radix Glycyrrhizae can supplement Qi,calomel can Sida of Qufushengji.About the drug dose:In the pills,total dose single drug in maximum for "coptis",followed by "rhizoma arisaematis","ginseng";In the electuary,total dose single drug in maximum for "calcitum",followed by "gastrodia elata","rhizoma typhonii";In the powers,total dose single drug in maximum for "radix sileris" and "Pharbitidis",followed by "Radix liquiritiae","prepared Radix Glycyrrhizae";In sublimed preparation,total dose single drug in maximum for "Radix Rehmanniae Praeparata" and "Radix Rehmanniae",followed by "radices ophiopogonis","figwort","radix asparagi".In the decoction,total dose single drug in maximum for "platycodon grandiflorum",followed by "coptis","Radix liquiritiae".In the total dose single drug,coptis,calcitum,Radix Rehmanniae,figwort and other heat-clearing medicine such as dose was still in the front row,radix sileris,gastrodia elata and other wind remedy,platycodon grandiflorum,rhizoma arisaematis,rhizoma typhonii and other "resolving Phlegm and relieving cough and asthma medicine",Pharbitidis is purgating drug,"Radix Rehmanniae Praeparata","ginseng","Radix liquiritiae","prepared Radix Glycyrrhizae","radices ophiopogonis","radix asparagi" and other tonifying Qi and tonifying Yin machine settings also centered on the dose level.4 "Xiaoeryaozhengzhijue" recorded in the original drug prescription:119prescriptions,"heat-clearing medicine" as monarch drug in 23 songs,followed by "resolving Phlegm and relieving cough and asthma medicine" as monarch drug in 19 songs,"purgating drug" as monarch drug in 12 songs,"sedative" as monarch drug in 8 songs,"releasing medicine" as monarch drug in 6 songs.In the 119 prescriptions,"heat-clearing medicine" as monarch drug is the most.5 "Xiaoeryaozhengzhijue" recorded in the compatibility principles of Drugs:in the original 119 prescriptions,there are a maximum of two herbs combined with the structure(i.e."medicine"),followed by "musk,cinnabar" is11 songs,"cinnabar,borneol" is 10 songs,"musk,borneol","musk,coptis" and "musk,bezoar" are 9 songs,"cinnabar,scorpio" and "borneol,bezoar" are 8songs,"cinnabar,bezoar","cinnabar,realgar" and "ginseng,prepared RadixGlycyrrhizae" are 7 songs,and so on.Compatibility of three herbs are for "cinnabar,borneol,musk" is 7 songs,"cinnabar,borneol,bezoar" is 6 songs,"cinnabar,musk,realgar" and "radices picrorrhizae,coptis,musk" are 5songs,"cinnabar,borneol,realgar","musk,borneol,realgar" and "cinnabar,scorpio,musk" are 4 songs.Four kinds of drug compatibility structure is the most "pyritum rotundum,cinnabar,borneol,musk","realgar,cinnabar,borneol,musk" and "radices picrorrhizae,pasta ulmi,coptis,musk" are only 4 songs.Five kinds of drug compatibility structure is the most "bezoar,realgar,cinnabar,borneol,musk",only 3 songs.The above results showed that,in the "xiaoeryaozhengzhijue" all prescription,compatibility between drugs for resuscitating with tranquilizer is the most common,drugs for resuscitating or tranquilizer combined with heat-clearing drugs,liver pacifying wind subduing medicine,helminthic and tonifying Qi is also quite a number of.Conclusions:1 Qian Yi was good at pediatrics,his academic thought can be summarized into 6 aspects:children are tender and lovely,treatment should be smooth;comprehensive analysis by the four examination methods,especially the inspection;based on the five internal organs,combine reinforcing and reducing;treatment according to syndrome differentiation,especially spleen and stomach;children are pure-yang constitution,make good use of clear method;do the right thing at the right time,good at pediatrics firstly.2 "Xiaoeryaozhengzhijue" contained 119 prescriptions,oral prescription111,topical prescription 8.All prescriptions involving a total of 189 herbs,among them,using the most is "heat-clearing medicine" 34 taste,then followed "asthma and eliminating phlegm" 12 taste,"liver pacifying wind subduing medicine" 11 taste,"releasing medicine" 10 taste,"astringent medicine" 10 taste.Composition of prescription drugs is the most "Qianghuo cream",23 herbs;herbs at least is the "Xiexin decoction","Antiperspirant powder","Firework cream","Baixiang pill","Niuli cream","Huisheng powder","Polygonum cuspidatum powder","Rhinoceros born mill juice",were taken orally,and taken topically "Arisaema powder",each have 1 medicine.Theresults show,Qian Yi pay attention to use heat-clearing medicine.3 "Xiaoeryaozhengzhijue" recipe has functions of "heat-clearing" are the most,followed by "expectorant" and "treat wind";indications with "heat syndrome",followed by "phlegm syndrome" and "wind syndrome".Musk and other drugs for inducing resuscitation,cinnabar and other drugs for sedative,coptis chinensis,indigo naturalis and other drugs for heat-clear was in the front row.The results show,Qian Yi attached great importance to the heat,wind,phlegm syndrome and the development important impact on disease,cure first heat method.4 The original prescription 1/5 with heat-clearing medicine as monarch,followed by asthma and eliminating phlegm medicine.This may suggest,Qian Shi in the treatment of fever,attach importance to the important significance of expectorant,make phlegm hot clear.5 Qian Yi diagnosis prescription,relied more on compatibility of inducing resuscitation,sedative and other drugs for heat-clear,musk,cinnabar,coptis chinensis,product is the most common of rhizoma coptidis.