Analysis Of Related Factors Of Clinical Diagnosis In Children With Recurrent Respiratory Tract Infections

Objective:To explore the characteristics of different types of recurrent respiratory tract infection and disease-related factors,for the early identification of recurrent respiratory tract infection type and to provide clinical basis for healing and preventing recurrent respiratory tract infections.Background and Method:Recurrent Respiratory Tract Infections(RRTIs)are common and frequently occurring in children.The etiology is complex,the disease is repeatedly delayed,a variety of factors together play an important role in the development of the disease.At present,there are few studies on the influence factors of repeated respiratory infection in different types of diagnosis.In this study,55 cases of children with recurrent respiratory tract infection who were treated in our hospital from April 2015 to June 2016 were divided into seven types of diagnosis according to the criteria of recurrent respiratory tract infection: repeated upper respiratory tract infection(group A),repeated tracheal bronchus(Group B),recurrent pneumonia(group C),repeated upper respiratory tract infection / repeated tracheobronchitis(group D),repeated upper respiratory tract infection / recurrent pneumonia(group E),recurrent bronchial bronchitis / recurrent pneumonia(group F),Repeated upper respiratory tract infection / repeated tracheobronchitis / recurrent pneumonia(group G).Through the questionnaire survey of children and their families,to understand the social characteristics of sociology,such as gender,age,whether premature birth,height,weight,pregnancy infection,feeding,feeding time,living habits,per capita housing area,family Whether the number of people who smoke,the number of smokers,the situation of care,allergy,family medical history,admission history,asthma history,clinical manifestations(runny nose,cough,wheezing,fever,etc.)have an impact on the type of diagnosis.And the relevant test results,such as chest X-ray,CT,immune function(IgA,IgM,IgG,CD3,CD4,subtype CD8,NK cells)were detected and recorded and analyzed,to understand the relationship between different types of the relevant examination and diagnosis.In addition,the treatment of RRTIs,such as the use of atomization,antibiotics,immune regulation,strengthen nutrition,tone up with physical exercise and so on,were analyzed.In addition,the children were followed up to find out the relationship between the follow-up time,the improvement of the diagnosis and the type of diagnosis.The data were recorded according to the relevant factors and analyzed by SPSS software.The count data were analyzed by X-chi-square test,where T <5 or n <40 using Fisher exact test,using logistic regression analysis of factors related to P <0.05 for the difference was statistically significant.Results:Among the 55 children with RRTIs,recurrent respiratory tract infections(group A,n=2),recurrent bronchitis(group B,n=16),recurrent pneumonia(group C,n=2),recurrent bronchitis / recurrent upper respiratory tract infection(group D,n=9),recurrent upper respiratory tract infection / recurrent pneumonia(group E,n=2),recurrent bronchitis / recurrent pneumonia(group F,n=20),recurrent upper respiratory tract infection / repeated bronchitis / recurrent pneumonia(group G,n=4)and the B group(29.09%),D group(16.36%),F group(36.36%).There were 39 males and 16 females with an average age of 3.05 ± 1.52 years.Among children with rrtis,preschool children were more common.Among children with rrtis of different types of diagnosis,gender(P = 0.768),age(P = 0.724)was not statistically significant.In the analysis of the factors influencing diagnosis of recurrent respiratory tract infection,including preterm birth(P=0.024),feeding(P=0.021)and feeding time(P=0.006)has an impact on the type of disease,and body weight(P=0.843),height(P=0.304),maternal infection(P=0.613)there was no significant difference between type and diagnosis.In addition,smoking(P=0.873),the per capita housing area(P=0.660),family income(P=0.702),allergic conditions(P=0.918),family medical history of allergy(P=0.296),in the case of(P=0.388),hospitalizations(P=0.251),history of asthma(P=0.854)there was no significant difference between the effects of the diagnosis of the disease type.In the clinical manifestations,children with recurrent upper respiratory tract infection were cough(23.63%),runny nose(38.18%)and nasal congestion(30.90%).Among the children with recurrent pneumonia,other symptoms(27.27%),Cough(25.45%),sputum and fever(18.18%),children with recurrent bronchial bronchitis,with cough(63.64%),sputum(63.64%)and fever(49.09%).In the aspect of detection methods,52 cases were examined by Immunology(pathogenic examination(n = 48),chest X-ray examination(n = 35),bronchoscopy and accessory respiratory support were less.The immune function test,immunoglobulin IgA,IgM,IgG,CD8,CD3 subtypes and NK cell abnormalities had no effect on the diagnosis of different types;and CD4 has a significant effect in the diagnosis of type group G,group D and group F.In the side of treatment,there are 47 cases of antibiotic treatment,effective in 43 cases;and 29 cases of aerosol treatment,effective in 27 cases.The follow-up time was mainly in 1-2 months.There was no significant correlation between follow-up and improvement.Conclusion:1.Preterm birth,feeding patterns and feeding time have different effects on different types of recurrent respiratory infections,and height,weight,maternal infection,smoking,per capita housing area,annual household income,entrustment,allergy,family medical history of allergies,admission history,history of asthma and other investigative factors have little effect on it.2.In clinical manifestations,cough in the repeated upper respiratory tract infection,repeated tracheal bronchus,recurrent pneumonia are relatively large,as the main symptoms,the need for timely control;another fever,sputum,etc.is the main manifestation of rrrtis.Through the early control of these clinical manifestations,can reduce the suffering of children,relieve family tension.3.In the treatment,antibiotics and atomization therapy is an effective way to treat children with rrtis,repeated upper respiratory tract infection;medicine and immune enhancement are the factors affecting the condition of the repeated upper respiratory tract infection,Repeated tracheal bronchitis,recurrent pneumonia have a positive impact.But lower immune is not good to disease improving.