Value Of NLR On Predicting The Long-term Mortality Of Patients With Acute STEMI Undergoing Primary Percutaneous Coronary Intervention: A Meta-analysis

Objective : To analyze the value of neutrophils/lymphocytes ratio(NLR)on predicting the long-term mortality of patients with acute ST-segment elevation myocardial infarction(STEMI)undergoing primary percutaneous coronary intervention(PCI)by meta-analysis.Methods : Both English and Chinese databases,including PubMed,Elsevier,Ebsco,Web of science,Wanfang database,CNKI database,VIP database,from their reception to February 2017 were searched to identify studies that reported relationship between NLR and the long-term mortality of patients with acute STEMI undergoing primary PCI.A standardized form and stata 12.0 software were used to extract information,and perform analysis.Results :10 clinical trials were included in this meta-analysis.The risks of long-term mortality(HR2.379,95%CI:2.035-2.782,P<0.001)were significantly higher in patients with high NLR compared patients with low NLR.After adjusting for other factors,the risks of long-term mortality(HR2.405,95%CI:1.862-3.106,P<0.001)were significantly higher in patients with high NLR compared patients with low NLR,too.Conclusions:Result from this meta-analysis show that the NLR could predict long-term mortality in patients with acute STEMI undergoing primary PCI.This finding needs to be validated by large-scale clinical trials in the future.