Correlation Analysis Of Multiple Factors In Patients Of Type 2 Diabetes Mellitus With Qi Deficiency Physique

Objective:To study the physical distribution of type 2 Diabetes Mellitus（T₂DM）inpatients in Kunming.To explore the distribution of clinical symptoms and syndromes in patients with T2 DM of Qi deficiency physique.To analyze the relationship between T2 DM patients of Qi deficiency physique and age,course of disease,symptoms,syndromes,check indexes.Methods:Collect the correlative data of T2 DM inpatients in Kunming Hospital of TCM,Yunnan Provincial Hospital of TCM and the first people’s Hospital of Yunnan Province during 2015.12--2016.12.The correlative data includes the patient’s name,gender,age,course of disease,body mass index（BMI）,fasting plasma glucose（FPG）,2h postprandial plasma glucose（2h PG）,hemoglobin A1c（Hb Alc）,fasting serum insulin（FINS）,triglyceride（TG）,uric acid（UA）,etc.Make case data into database with Excel software and SPSS20.0 statistical software is used for statistical analysis.Chi square test is used for the enumeration data.Independent sample T test and x ±s are used for the measurement data in accordance with the normal distribution.Independent sample T test and median are used for the measurement data in accordance with the skewness distribution.Two stepwise Logistic regression analysis are used for correlation study.Result:1.The physiques of the 297 inpatients with T2 DM in this study is normal constitution16.16%,biased constitution 83.84%.The permutation sequence of various physique in biased constitution from high to low order is:Qi deficiency constitution 27.3%,Yin deficiency constitution 22.5%,blood stasis constitution 17.7%,Yang deficiency constitution 12.9%,damp heat constitution 8.4%,phlegm dampness constitution8.0%,Qi stagnation constitution 2.0%,special constitution1.2%.2.The main symptoms and signs of inpatients with T2 DM of Qi deficiency physique are:dry mouth,fatigue,insomnia,thirst,sweating,tongue veins tortuous and dizziness,leg pain,night sweats,backaches.It has significant difference between Qi deficiency group and non Qi deficiency group in the symptoms of dry mouth,fatigue,insomnia,sweating and lumbago（P < 0.05）.3.The order of TCM syndromes distribution about inpatients with T2 DM of Qi deficiency physique from high to low is:Qi-Yin deficiency 70.59%,phlegm turbidity42.65%,blood stasis 35.30%,Yin deficiency of liver and kidney32.35%,Yin-Yang deficiency 22.06%,excessive heat consuming body fluid20.59%,phlegm（damp）heat accumulation 8.82%.It has significant difference between Qi deficiency group and non Qi deficiency group in TCM syndromes including excessive heat consuming body fluid and Qi-Yin deficiency（P < 0.05）.4.It has significant correlation（P<0.05）between T2 DM patients with Qi deficiency physique and Qi-Yin deficiency（P=0.002,OR=3.301）syndrome,fatigue（P=0.002,OR=2.998）,sweating（P=0.027,OR=1.928）,lumbago（P=0.006,OR=0.438）.It has no significant correlation（P>0.05）between T2 DM patients with Qi deficiency physique and age,course of disease,blood pressure,body mass index,waist circumference,blood glucose,hemoglobin A1 c,insulin resistance index,insulin secretion function index,blood lipid.Conclusion:1.In Kunming,the TCM constitution types of T2 DM inpatients are mainly Qi deficiency and Yin deficiency.2.The primary clinical symptom of T2 DM inpatients with Qi deficiency physique is Qi deficiency symptoms,and the secondary symptoms are Yin deficiency symptoms and blood stasis symptoms.3.The primary TCM syndrome of T2 DM inpatients with Qi deficiency physique is Qi-Yin deficiency,and the secondary syndromes are phlegm turbidity,blood stasis,Yin deficiency of liver and kidney.4.The T2 DM inpatients with Qi deficiency physique is easy to appear fatigue and sweating,and easy to form Qi-yin deficiency syndrome,and has no significant correlation with biochemical index.