Analysis Of Measles Spatial Distribution And Investigation Of Case Infection Site In Anhui Province,2016

Objective: In order to provide the basis for blocking the spread of measles,explore the spatial-temporal distribution of measles from February to May in Anhui province,2016,investigate case information and infection sites in high-occurrence season and explore epidemiological links of which factors affecting the spread of the virus.Methods: Epidemiological data of measles from February to May were collected and used to establish a database of Geographic Information System(GIS).Geo Da 1.4.6 and Sa TScan9.1 were used to conduct visualization of morbidity and spatial-temporal scan analysis.The measles epidemiological survey were designed to telephone measles confirmed cases about general information?activity history before 7 ~21 days of onset day and vaccination history.Results: 1.416 cases of confirmed measles cases were reported,of which cases reported by Anhui province were 362,accounting for 87.01%.Others were mainly reported by Nanjin and Xuzhou.Weekly incidence had a dramatic fluctuation,but at a rising trend generally.2.The morbidity map showed that incidence rate of Q iaocheng from Bozhou,Dangshan from Suzhou,areas around Hefei and C hizhou are higher.Three spatial-temporal clusters were identified by the spatial-temporal scan analysis,which were located in Q iaocheng from March to May,areas around Hefei from mid March to mid May,and some districts in Huangshan and C hizhou from mid to late May.3.353(84.85%)measles cases were investigated,of which cases infected from other provinces mainly from Jiangsu?Beijing and Henan.4.There were 211 children below 15 years old of which 58 cases(27.49%)were below 8 months old,32 cases(15.17%)vaccinate on time and 121 cases(57.34%)qualified vaccination didn't vaccinate on time.And there were 5 cases sick less than 15 days after vaccination.5.Nosocomial infection and out of hospital infection had no significant difference in gender distribution but did have in age distribution.There was a significant difference in the distribution of gender and age among the patients with nosocomial infection.Nosocomial infection occurred mainly in three level and two level hospitals.6.There defined 19 times of epidemiological links among surveyed cases,most of which were caused by close contacting with acquaintances like friends,neighborhoods,colleagues and families.7 mothers and sons were suffering from measles at the same time.6 health medical workers were infected with measles.Conclusions: 1.Measles in Anhui from February to May,2016 were clustered geographically.Regional incidences had obvious differences.2.The number of cases of nosocomial infection and out-of-hospital infection was similar.3.Nosocomial infection occurred mainly in three level and two level hospitals.4.Young age groups had more nosocomial infection than out-of-hospital,while older age groups had less nosocomial infection than out-of-hospital.5.Young age group of men were more than women,while older age group were the opposite.6.Vaccination is a leading cause accounting for childhood morbidity.7.Many cases failed to be diagnosed at the initial stage,which would not effectively controlled infection source.