Compound Thirty-seven Particles Agaitnst Clinical Study Of Atherosclerosis And Its Related Inflammatory Factors

Objective By observing the compound particles notoginseng for atherosclerosis(atherosclerosis,AS)before and after treatment in patients with clinical symptoms and serum white blood cells,allergic C-reactive protein(hypersensitive C-reactive protein,the hs-CRP),the change of blood lipid and related inspection,to evaluate the clinical curative effect of compound particles notoginseng treatment AS,at the same time to explore its action mechanism.Method1.According to western medicine diagnostic criteria for selection of atherosclerosis in patients with atherosclerosis(kidney and blood stasis type)40 cases,adopt the method of randomized,controlled it can be divided into research group and the control group(n=20).2.The team give atorvastatin calcium,aspirin and compound particlesnotoginseng,while control group only use of atorvastatin and aspirin,treatment for 8 weeks.3.The detection of serum white blood cells before and after the treatment,allergic C-reactive protein(hs-CRP)and blood lipid levelof change;The change of the carotid intima-media thickness;The change of clinical symptoms observation record;do the doctor of traditional Chinese medicine symptom integral comparison.All measurement data to "(x|-)±s",said the group t test for pairedata,is compared between the two groups compare with independent sample t-test,count data with ? squared test,P<0.05 for the difference was statistically significant,P<0.01 for the difference is significant statistical significance.All materials used SSPSS17.0statistical software for statistical analysis.Result1.The team before and after treatment comparison: after treatment serum levels of white blood cells,allergic C-reactive protein(hs-CRP)and blood lipid levels were significantly lower,carotid intima-media thickness decreases,and relieve clinical symptoms,the doctor of traditional Chinese medicine symptom integral decreased,compared with before treatment there was a significant statistical significance difference(P<0.01).2.The control group before and after treatment comparison: after treatment serum levels of white blood cells,allergic C-reactive protein(hs-CRP)and blood lipid levels were significantly lower,carotid intima-media thickness decreases,and relieve clinical symptoms,the doctor of traditional Chinese medicine symptom integral,there are significant difference compared with before treatment(P<0.01).3.The research group compared with the control group after treatment,after treatment serum white blood serum white blood cells,allergic C-reactive protein(hs-CRP)and blood lipid levels drop degree of theteam are better than that of control group(P<0.05);Two groups of carotid intima-media thickness are falling,the team fell more obvious(P<0.05);two groups of clinical symptoms were improved aftertreatment,the degree of group than the control group improved more significantly(P<0.01);degree of symptom integral aspect of traditional Chinese medicine group than the control group to reduce(P<0.01);two groups of treatment effect are relatively smooth,does not appear obviousadverse reactions.Conclusion1.The compound particles notoginseng can obviously reduce the serum white blood cells of patients with atherosclerosis,inflammatory2.Compound notoginseng particles to improve the mechanism of action of atherosclerosis in patients with clinical symptoms may be related to itsanti-inflamematory,lipid and stable plaques.