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Study On TCM Syndrome Differentiation And Correlation Of Evaporative Dry Eye

Posted on:2018-06-07Degree:MasterType:Thesis
Country:ChinaCandidate:Y L GuFull Text:PDF
GTID:2334330515467929Subject:Traditional Chinese Medicine
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Purpose:Evaporative dry eye is a common eye ocular surface disease,it is falling tears or abnormal tear film stability dynamics caused by abnormal,and accompanied by eye discomfort,and(or)a disease of ocular surface damage.The abnormal lipid layer is the disease produce development the core,usually caused by abnormal lipid layer factors may lead to evaporative dry eye.Traditional Chinese medicine believes that this disease is due to loss of blood and body fluid in five Ruyang not on the wing in the head,the eye loses moisture and cause.However,the only dry eye syndrome research and analysis of evaporation dry eye is too strong.No study of syndrome differentiation.Based on the above,this study aims to carry out the prospective study to explore TCM EDE type,age,gender,time use video terminal,ametropia,wear contact lenses,sleep time,corneal refractive surgery,air conditioning room time,the correlation between meibomian gland function.Factors and TCM Syndrome type,provide an objective basis for the combination of traditional Chinese and Western medicine treatment and prevention of EDE.Methods:From April 2016 to February 2017 in Jiangsu Province Traditional Chinese Medicine Hospital,102 cases diagnosed as evaporative dry eye patients as the research object,recording the age,gender,time use video terminal,ametropia,wear contact lenses,sleep time,corneal refractive surgery,the use of air conditioning time,tear secretion test(S I t),tear break-up time(BUT),corneal fluorescein staining(FL),meibomian gland function score,and according to the local and systemic symptoms,tongue and pulse combination,four diagnostic methods,syndrome differentiation,and analysis between the syndrome and the clinical data Statistical analysis was performed using SPSS 20.0Result:(1)the TCM syndrome type of blood deficiency and wind dryness,at most,a total of 25 cases,accounting for 24.5%,followed by Yin deficiency and dampness syndrome>>liver kidney yin deficiency syndrome of spleen stomach damp heat syndrome>wind heat assailing>evil heat nostalgia card,respectively 23 cases,18 cases,16 cases,12 cases and 8 cases.The lung yin deficiency in no case.(2)there were more women in this disease,male and female in 73 cases.The ratio of male to female was 1:2.52.Sex has nothing to do with TCM syndrome type.(3)the disease age distribution in 20 to 35 years and 45 to 50 years old.The age and the TCM syndrome type had significant difference,P=0.008(P<0.01),spleen and stomach damp heat syndrome,yin deficiency and dampness syndrome mainly in young and middle-aged group,and concentrated in the liver and kidney yin deficiency syndrome in middle-aged and elderly patients,blood deficiency and wind dryness and wind heat assailing concentrated in the young group.(4)evaporative dry eye patients with ocular symptoms of frequency from high to low were dry in 96 cases(94.1%),visual fatigue in 89 cases(87.3%),foreign body sensation in 74 cases(72.5%),68 cases(66.7%),itching,photophobia,56 cases(54.9%)of 56 cases(on the eyelids 54.9%),with 55 cases(53.9%),55 cases(53.9%),stinging tears in 51 cases(50%),48(47.1%)cases of fluctuations in vision,45 cases(44.1%eyes),burning frequency in 43 cases(42.2%),an inflammatory secretions of 38 cases(37.3%).There were significant differences in tears and syndrome,P=0.017(P<0.05),liver kidney yin deficiency syndrome,88.8%patients without symptoms and syndromes.With tears had significant difference.P=0.028(P<0.05),the evil heat nostalgia syndrome,87.5%patients with symptoms.The secretion of inflammatory and syndrome types have significant difference P=0.042,(P<0.05),spleen and stomach damp heat syndrome,68.75%patients with inflammatory secretions.On the eyelids and syndromes are statistically significant,P=0.003(P<0.01),yin deficiency and dampness syndrome in 82.6%patients had severe symptoms of upper eyelid,and other symptoms were not statistically different(P>0.05)(5)sleep time and TCM syndrome type were statistically different,P=0.002(P<0.01),pathogenic heat retention syndrome patients sleep longer,generally greater than 8.5 hours.(6)S I T,BUT,FL and TCM syndrome type were not statistically different,P were>0.05.(7)grey line position and TCM syndrome type had significant difference,P=0.003(P<0.01),dhsss,gray line position of the highest score,blood deficiency and wind dryness gray line the lowest score.Meibomian secretion and TCM syndrome type had significant difference,P=0.000(P<0.01),spleen stomach damp heat syndrome and liver kidney yin deficiency syndrome in meibomian gland secretions,higher scores,and the passage of heat syndrome and blood deficiency and wind dryness score low.Meibomian gland deletion and TCM syndrome type had significant difference,P=0.010(P<0.01),spleen stomach damp heat syndrome and liver kidney yin deficiency,meibomian gland loss score was the highest.(8)There was no significant difference between syndrome classification and TCM syndrome differentiation,P=0.410(P>0.05).Conclusion:Evaporative dry eye syndrome differentiation has certain characteristics,mainly divided into blood deficiency and wind dryness syndrome,yin deficiency and dampness syndrome,liver kidney yin deficiency,spleen stomach damp heat syndrome,wind heat syndrome and heat syndrome hit nostalgia,etiology and pathogenesis is deficiency of yin and blood,rheumatism heat disturbance,eyes losing nutrition and disease involving the liver and kidney viscera.The spleen and stomach.The disease is more common in females,regardless of gender and age.The syndrome type of traditional Chinese medicine and traditional Chinese medicine typing.Tears,with inflammatory secretions,on the eyelids and typing of TCM.Sleep with TCM syndrome type.SI t,BUT FL,has nothing to do with the TCM syndrome type.Meibomian gland function associated with TCM syndrome.Symptoms classification and TCM type no Close.
Keywords/Search Tags:evaporative dry eye, ocular surface disease, TCM syndrome differentiation, prospective study, correlation analysis
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