Study On The Relativity Between Distribution Of Syndrome Type In TCM Of Diabetes And Ankle Brachial Index And Hemorheology

Objective:To study the distribution of TCM syndromes of Type 2 Diabetes and the relativity between different TCM syndrome type and Hemorheology and Ankle Brachial Index,provide laboratory reference for normalized classification of TCM syndrome type and provide theoretical basis for prevention and treatment of vascular complication(such as arteriosclerosis)of Type 2 Diabetes patients.Methods:120 Patients with Type 2 Diabetes,who are selected from April 2016 to August 2016 in Wuxi Traditional and Western Hospital Endocrinology and in line with the 2013 China Association of TCM diagnostic criteria and 1999 WHO classified criteria.TCM syndrome type are in accordance with 2002 Ministry of Health,Traditional Chinese Medicine for Clinical Research,including yin and both qi and yin deficiency,vein blood stasis,excessive heat,and both yin and yang deficiency syndromes.50 cases of normal group are set as contrast group.General clinical data of both group such as name,age,sex are collected and blood glucose,hemorheology,and ankle brachial index among different groups are analysed.Results:1.Syndrome classification of Type 2 diabetes patients(from low to high):both yin and yang deficiency(17.5%)less than excessive heat(23.3%)less than vein blood stasis(26.7%)both qi and yi deficiency(32.5%).2.TCM syndromes group of T2DM,the course of disease with the excessive heat,qi and yin deficiency group,vein blood stasis group,yin and yang deficiency group increased;which excessive heat group has the shortest duration,and yin and yang deficiency group has the longest.There was significant difference between the other groups(P<0.05,P<0.01).The levels of fasting blood glucose were significantly higher than those of the patients with qi and yang.HbAlc levels with the excessive heat,qi and yin deficiency group,vein blood stasis group,yin and yang deficiency group increased;comparison with each other,which qi and yin deficiency group and yin and yang deficiency group,blood stasis.There was no significant difference between the two groups.3.The right and left ankle brachial index was associated with the blood stasis group,the yin and yang deficiency group,the excessive heat group,the normal control group and the qi and yin deficiency group.The ankle brachial index of blood stasis group and yin and yang deficiency group were lower,There was significant difference between the two groups(P<0.05).The blood stasis and the normal control group and the other TCM syndromes group were statistically significant differences(P<0.01).4.Compared with the normal control group,hemorheology of T2DM group is higher,the difference was statistically significant(P<0.05),and the two groups had significant statistical significance in whole blood viscosity(high cut),capillary plasma viscosity and erythrocyte sedimentation rate(P<0.01).Among the TCM syndromes of T2DM,the whole blood viscosity(low cut),whole blood viscosity(high cut),capillary plasma viscosity,erythrocyte sedimentation rate,hematocrit and erythrocyte aggregation index,both qi and yi deficiency,excessive heat,both yin and yang deficiency and vein blood stasis increased.There was significant difference between the each other groups(P<0.05,P<0.01).in conclusion:1.Qi and Yin Deficiency Syndrome for type 2 diabetes is the most common TCM syndromes,followed by blood stasis,excessive heat,the number of cases of yin and yang deficiency at least.2.Type 2 of diabetes in patients with duration and blood glucose levels from low to high,followed by excessive heat,both qi and yin deficiency,blood stasis,both yin and yang deficiency syndrome,glycosylated hemoglobin and glycated serum protein the lowest level,the highest yin and yang deficiency,type 2 diabetes longer duration,the condition gradually increased.3.Type 2 of diabetes patients with both right and left ankle brachial index from high to low,followed by blood stasis group,both yin and yang deficiency,excessive heat,qi and yin deficiency;The ankle brachial index of the blood stasis group was the lowest.The ankle brachial index can be used as one of the reference of arterial disease and indicators chronic occlusion of diabetic atherosclerosis and so on.4.Among the type 2 diabetes patients,the hemorheological indexes of the patients with diabetes mellitus were abnormally increased from low to high,followed by qi and yin deficiency,excessive heat,both yin and yang deficiency,blood stasis group.Blood stasis pulse of the blood rheology indicators of the highest indicators of hemorheology can be used as the prevention and treatment of diabetes mellitus and one of the quantitative indicators of diabetic vascular complications,especially;blood stasis throughout the development of diabetes,appropriateclinical application of blood circulation therapy to improve the complications of diabetes and the prognosis is important.