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The Clinical Significance Of Ankle-brachial Index In The Diagnosis Of Peripheral Artery Disease And Its Application Of The Risk Factors Analysis In The Patients With Type 2 Diabetes

Posted on:2008-08-20Degree:MasterType:Thesis
Country:ChinaCandidate:Y GuanFull Text:PDF
GTID:2144360218959868Subject:Internal Medicine
Abstract/Summary:PDF Full Text Request
The clinical significance of ankle-brachial index in the diagnosis of peripheral artery disease and its application of the risk factors analysis in the patients with type 2 diabets.ObjectiveTo investigate the anlde-brachial index (ABI) in the diagnosis of periph-eral artery disease (PAD) and its relationship with the cardiovascular risk factors in the patients with type 2 diabetes. To investigate the relevant risk factors of blood vessel disease in case with type 2 diabetes.MethodsABI was examined in the 96 patients with type 2 diabete, with English ES-1000 Doppler diagnostic instrument of blood vessel. The patients were divided into group A(ABI(?)0.9)and group B(ABI<0.9). Age, diabetes duration, glucose, dyslipidemia, HbA1C were recorded .The relationship of ABI with the other risk factors of blood vessel disease in case with type 2 diabete was analyzed by bivariate analysis and blood vessel disease in case with type 2 diabete.multivariate Logistic regression. T-test used in participants having risk factors vs the inverse. The risk factors of blood vessel disease in case with type 2 diabete include age, sex, hypertension, high levels of total cholesterol, high levels of fasting plasma glucose, low levels of high-density lipoprotein cholesterol, overweight or obesity, smoking habit etc.ResultsBy bivariate analysis, the ABI is associated with sex, body mass index(BMI), diastolic blood pressure(DBP), total cholesterol(TC), high-density lipoprotein cholesterol (HDL-C), smoking habit. Analyzed by multivariate logistic regression, factors that mainly influence the ABI include sex, age, hypertension and smoking habit. Among the herd of the elders ((?)60 years old), Smoking, age in men and hypertension in women is a powerful influencing factor of ABI. Mean ABI value±standard deviation were significant in the groups having risk factors of overweight or obesity(p=0.02), low levels of HDL cholesterol (p=0.04) and smoking habit (p<0.0001). No differences of mean. ABI exist in subjects having hypertension, high levels of total cholesterol and high levels of fasting plasma glucose compared with non-hypertension, non-high levels of total cholesterol and non-high levels of fasting plasma glucose.Analyzed by multivariate logistic regression, factors that mainly influence the ABI include sex, age, hypertension and smoking habit. Smoking, age in men and hypertension in women is a powerful influencing factor of ABI.ConclusionsChecking of ABI can reflect the ischemic degree of lower limbs and direct doctor to select theraputic method and judge the curative effect. It can be accept easily by patients because of cheap, repeatable and non-invasive character.
Keywords/Search Tags:Ankle-brachial index, Diabetes mellitus, Peripheral artery disease
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