The Study Of TiaoXinShuGanJianPi Decoction In The Treatment Of Irritable Bowel Syndrome Type Diarrhea

ObjectiveIrritable bowel syndrome(irritable bowel syndrome,IBS)is a common clinical gastrointestinal functional disease,with abdominal pain,abdominal distention,abnormal changes in bowel habit and defecate character as the main clinical symptoms,which persistently or intermittently attack.IBS can be roughly divided into diarrhea,constipation,alternating diarrhea and constipation,abdominal pain.Complex cause of disease,multiple clinical symptoms,high incidence and unclear pathogenesis are the characters of IBS.There is no a drug that can effectively relieve all symptoms,combined with poor effect of pure medicine treatment and high recurrence rate,so we need to take a comprehensive one and follow the principle of individualization.This study is to observe the effect of treatment of IBS type diarrhea with empirical formula of tutor,diet guidance and psychological counseling.We hope that we can preliminarily work out a comprehensive treatment with TCM characteristics that is expected to improve the symptoms of IBS patients and the life quality.MethodsThis study of 60 patients with IBS type diarrhea were randomly divided into treatment group and control group,30 cases in each one.Patients of treatment group took TiaoXinShuGanJianPi decoction twice a day.In the control group,30 patients took trimebutine maleate table 0.1g three times a day.Two groups were given diet guidance and psychological counseling.Abdominal pain and discomfort,defecate,associated and emotional symptoms(refer to Suzhou in 2010,"gastrointestinal diseases in TCM symptom scale" formulated by combining Chinese and Western medicine committee of digestive system.Hamilton anxiety scale)were respectively assessed before and after the treatment,comparing the influence of two groups in the TCM symptoms and life quality.ResultsTiaoXinShuGanJianPi decoction cooperated with psychological counseling and diet guidance,which can effectively slow down the intestinal peristalsis,improve intestinal absorption,repair the intestinal mucosa,lower the height of visceral sensitivity,regulate gastrointestinal flora,improve anxiety depression and sleep quality of patients.This decoction may cure the root cause of disease and symptoms,giving consideration to many aspects.The treatment group total effective rate was 93.3%,while the control one was 66.7%.The former was superior to the latter,with statistical significance(P<0.05).ConclusionThis research according to "doctrine of five zang organs" thinks "heart mastering five zang" and "heart controlling mental activities".In the study,calming mental activity is regarded as the basic therapeutic principle,it also take stagnation of liver qi and nutrition of spleen qi into account.When we make a prescription,we always use some drugs that meet our therapeutic principle.Besides,fully attached great importance to the mental and dietary factors,there therapies are in coordination with drugs.In a word,this treatment can effectively relieve the clinical symptoms of IBS type diarrhea,improve the quality of life,reduce the recurrence rate and adverse reaction,exceed trimebutine maleate table,providing a comprehensive therapy with TCM characteristic for curing IBS type diarrhea.