Related Research About TCM Syndrome Of Essential Hypertension In Patient With Brachial-ankle Pulse Wave Velocity And Carotid Atherosclerosis

Objective:To observe the correlations between TCM syndromes of essentional hypertension and baPWV,IMT,plaque in carotid atherosclerotic,plaque stability,and blood lipids,to provide a scientific basis for TCM of differentiation objective and treatment of standardized objective with essential hypertension.Method:This restrospective study collected 121 patients with essential hypertemsion who were divided into hypertensive group and made out syndrome differentiation according to the clinical materials.And selected 31 cases with normal blood pressure as the normal blood pressure group.All the cases made carotid artery Doppler Ultrasonography,arteriosclerosis testing,blood lipid testing,and recorded baPWV,IMT,carotid atherosclerotic plaque incidence,plaque stability,and the lipid index.Results:1.To arrange four TCM syndrome patterns of essential hypertension according to their constitute ratio in order:the excessive phlegm-dampness type(52.07%)>the liver-fire hyperactivity type(18.18%)>the yin-yang deficiency(16.53%)>the yin deficiency and yang hyperactivity type(13.22%).2.In terms of gender,four TCM syndrome types have significant statistical differences:the patient consists mostly of male in the liver-fire hyperactivity type and the excessive phlegm-dampness type,while female in the yin and yang deficiency type and the yin deficiency yang syndrome type.3.The excessive phlegm-dampness type and the liver-fire hyperactivity type are major patterns in grade of 1 EH;the yin deficiency and yang hyperactivity type is major pattern in grade of 2 EH;and the yin-yang deficiency type is major pattern in grade of 3 EH(P<0.05).4.In terms of age,the liver-fire hyperactivity type is mainly distributed in less than 50 years old,The excessive phlegm-dampness type is mainly distributed in 50 to 60 years old,the yin deficiency and yang hyperactivity type is mainly distributed in 60 to 70 years old,and the yin-yang deficiency type is mainly distributed in more than 70 years old(P<0.05).The course ofTCM syndromes is as follows:the yin-yang deficiency type>the yin deficiency and yang hyperactivity type>the excessive phlegm-dampness type>the liver-fire hyperactivity type(P<0.05).5.The distribution of baPWV value is as follows:the yin-yang deficiency type>the phlegm-dampness syndrome type,the yin deficiency and yang hyperactivity type>the liver-fire hyperactivity type>the normal blood pressure group(P<0.05).The IMT index of the liver-fire hyperactivity type was lower than other three syndromes(P<0.05).6.73 cases of the 121 hypertension also suffer from dyslipidemia.it is up to 60.33%.the regularity of TCM syndromes is as follows:the phlegm-dampness syndrome type(71.43%)>the liver-fire hyperactivity type(63.64%)>the yin-yang deficiency type(50%)>the yin deficiency and yang hyperactivity type(25%).There is significant differences between TCM syndromes and dyslipidemia among 73 patients with hypertension(P<0.05).The TC level is highest in the phlegm-dampness syndrome type during four syndromes;The LDL-C level is higher in the phlegm-dampness syndrome and the yin-yang deficiency type during four syndromes.The HDL-C level is highest in the the yin deficiency and yang hyperactivity type during four syndromes(P<0.05).There is no significant differences between TCM syndromes and TG(P>0.05).7.The highest rate of carotid plaque formation is the phlegm-dampness syndrome type during four syndromes(P<0.05),Mainly with soft spots and mixed.Conclusions:1.The excessive phlegm-dampness type is the most widely distributed in hypertension TCM distribution.2.The type of TCM syndromes is closely related with the age of patients,the course of the EH,and the blood pressure levels.3.The BMI index of the phlegm-dampness type syndrome is the highest among four syndromes,dyslipidemia is up to 71.43%,especially the level of TC and the LDL-C,which can be used as one of the objective indicators in the phlegm-dampness patients with hypertension.4.The degrees of plaque in carotid atherosclerotic is the highest in the phlegm-dampness syndrome type during four syndromes,Mainly with soft spots and mixed.the degrees and numbers of plaque in carotid atherosclerotic can be used as one of the objective indicators in the phlegm-dampness patients with hypertension.5.The baPWV value was the fastest in the yin-yang deficiency type during four syndromes,which can be used as one of the objective indicators in the yin-yang deficiency patients with hypertension.6.The phlegm-dampness syndrome is high-risk type about carotid atherosclerosis,the yin and yang deficiency syndrome is high-risk type about atherosclerosis,we should take them seriously.