Research On The Pattern Of TCM Syndromes Distribution In Chronic Ulcerative Colitis

Objective:To investigate the relationship between different TCM syndromes of ulcerative colitis and factors such as course,scope of lesions,clinical types,stage, colonoscopy mucosa expression,endoscopic index,and histopathological grade.so as to conclude the Pattern of syndromes distribution,provide an objective basis For ulcerative colitis syndrome differentiation.And then summed up the evidence of this disease type distribution to provide guidance for the prevention and treatment of UC.Methods:summarize the clinical data as well as information on Colonoscopy of 169 cases of UC patients.On the collation of data collected,we use the statistical software spss 16.0 conduct Pearson correlation test(Pearsontest).Analysis the influence of age, course,scope of lesions,clinical types,stage,colonoscopy mucosa expression, endoscopic index,and histopathological grade on the pattern of syndromes distribution.Results:The frequency of occurrence of different syndromes were found to be large intestine dampheat type＞spleen qi deficiency type＞spleen qi deficiency and dampheat type＞spleen-Kidney Yang Deficiency＞qi and blood stasiss＞liver stagnation and spleen deficiency＞yin and blood deficiency.Young people mainly in spleen-stomach dampheat type,middle-aged mainly in the spleen and stomach weak evidence-based,the elderly mainly spleen and kidney yang deficiency weak evidence and the spleen and stomach qi deficiency type.Initially type of UC patient mainly express spleen-stomach dampheat type (damp-heat syndrome),chronic relapsing type mainly express hot and humid for the coexistence of spleen deficiency,chronic persistent type mainly express for both spleen and kidney qi deficiency(Deficiency).Mild mainly express spleen-stomach dampheat type,medium mainly express to spleen-stomach dampheat and the spleen and stomach deficiency.severe mainly express to qi and blood stasis,spleen and Kidney Yang Deficiency.Lesion in the rectum and sigmoid colorectum accounted for straight B 52.07%, mainly in spleen-stomach dampheat type,left colon accounted for 12.43%,mainly in the spleen and stomach weakness type and spleen-stomach dampheat type,sub-total colectomy accounted for 5.92%,mainly in qi and blood stasis type,full colon accounted for 29.59%,mainly in both the qi and blood stasis type and spleen and Kidney Yang Deficiency type.The activity period was particularly prevalent in the large intestine damp-heat syndrome,weak spleen and stomach deficiency-heat Syndrome card,the remission period was particularly prevalent in the weak spleen and stomach,spleen and Kidney Yang Deficiency Syndromes and spleen qi deficiency and dampheat type。Ulcerative colitis in endoscopic typeⅠmainly in spleen-stomach,dampheat type and spleen and stomach weakness type,Spleen Damp-Heat Syndrome rare,the difference was significant;endoscopic classification typeⅡmainly in spleen-stomach dampheat typ and spleen qi deficiency and dampheat type;endoscopic classification of typeⅢmainly in qi and blood stasiss type and spleen and stomach weakness type. ulcerative colitis mucosal histology examination period activity was particularly prevalent in the large intestine damp-heat syndrome,weak spleen and stomach deficiency-heat Syndrome card,the remission period was particularly prevalent in the weak spleen and stomach,spleen and Kidney Yang Deficiency Syndromes and spleen qi deficiency and dampheat type。Between the seven Syndromes of UC,the endoscopic index of intestine dampheat type,spleen qi deficiency type,spleen qi deficiency and dampheat type are higher than others.The severity of histological gradeⅠlevel are mainly seen in the large intestine damp-heat syndrome,Ⅱ-level are mainly seen in the spleen and stomach qi deficiency type and large intestine damp-heat syndrome,Ⅲ-class are mainly seen in the large intestine damp-heat of spleen and the kidney yang deficiency type.large intestine damp-heat syndrome,spleen and stomach qi deficiency type and spleen qi deficiency and dampheat type are mainly seen in histological gradeⅡlevel,spleen and the kidney yang deficiency type,qi and blood stasiss type are mainly seen in histological gradeⅢlevel.Conclusion:In this study,There was a significant correlation between different TCM syndromes of ulcerative colitis and scope of lesions,clinical types,stage,colonoscopy mucosa expression,endoscopic index,and histopathological grade.Observation of the above indicators as well as colonoscopy can be used as an extension of Inspection applies to clinical,and provide strong indicators of the objective for the TCM.The occurrence and development of ulcerative colitis,are the result of intrinsic deficiency and the extrinsic virtual acting on the human body.The intrinsic deficiency marked by spleen qi deficiency,the extrinsic virtual marked by spleen-stomach dampheat type.It can be seen in the clinical treatment of UC,we should pay attention to staging and rule,the combined treatmentof overall and local lesion,intrinsic and extrinsic lesion as well as to follow the principle of individualized treatment.