This TyPe Dehumidifying SPleen Decoction And Dampness Yun The Clinical Observation Of Chronic Eczema And Interferon-? The Influence Of The Level Of Interleukin-4

Objective:Watch this tyPe dehumidifying sPleen decoction and damPness yun the clinical curative effect of chronic eczema.While detecting chronic eczema Patients before and after treatment serum immune cytokine exPression,ComParative analysis of the changes before and after the treatment,In order to exPound this desiccant sPleen decoction and damPness yun tyPe chronic eczema clinical curative effect and mechanism of action,Provide a new drug for clinical treatment of chronic eczema and train of thought.Methods:In the first affiliated hosPital of guangxi medical university dermatologist clinics recruited 60 cold damPness aggregates the sPleen in Patients with chronic eczema,Were randomly divided into treatment grouP and control grouPThe.treatment grouP to be exPlored dehumidification souP,A daily dose,Mianjian granule(Jiangyin Production day jiang Pharmaceutical co)Warm water,400 ml Points two internal and in the morning and at night.The control shall be left cetirizine hydrochloride caPsules(SPecifications for 5 mg/tablet,Produced by hunan nine standard Pharmaceutical co,H20060183 aPProved by the state)One tablet each time,warm water to drink,once a day.Treatment for 28 daysfor a Period of treatment,a total of a course of treatment.In EASI before and 4 weeks treatment,VAS,evaluation of quality of life,chronic eczema and quality of life scale body of TCM syndrome integral score,In the third month after treatment for relaPse.Treatment of the Patients were observed before and after PeriPheral blood interleukin-4,interferon-?,evaluate the clinical efficacy.Results: ComPared with control grouP EASI integral before and after the treatment,treatment grouP differences were statistically significant(P<0.05).Treatment grouP and control grouP before and after treatment of TCM syndrome integral body comParison,the differences were statistically significant(P<0.05).4 weeks after treatment,the treatment grouP total effective rate was 86.66%,the control grouP was70%,the treatment grouP comPared with the control grouP total effective rate difference had statistical significance(P<0.05).Recurrence rate were followed uP for 3 months,the treatment grouP was obviously lower than the control grouP recurrence rate,the differences were statistically significant(P<0.05).In the two grouPs after treatment in Patients with PeriPheral blood Pure interleukin-4 levels are lower,the level of interferon-?,differences were statistically significant(P<0.05).ComParing the two grouPs after treatment,the treatment grouP of PeriPheral blood Pure interleukin-4 is lower than the control grouP,interferon-? levels higher than the control grouP,difference has statistical significance(P<0.05).Conclusions:1This desiccant souP treatment curative effect is cold damPness aggregates s Pleen syndrome of chronic eczema,Significantly better than the left cetirizine hydrochloride in the control grouPTo,imProve her lesions in Patients with signs,Ease the Patients clinicalsymPtoms,ImProve the Patients quality of life,etc,Effect is remarkable.2This adjustable dehumidifier souP PeriPheral blood interleukin-4,interferon-? levels.