The Clinical Observation Of Jiawei Houpu Mahuang Decoction In The Treatment Of Acute Exacerbation Of Asthma With Frigiopyretic Asthma

Objective:Using randomized controlled methods,clinical research on treatment of frigiopyretic asthma of Jiawei Houpu Mahuang Decoction and the influence of pulmonary function and fractionalexhaled nitric oxide(FeNO).Method:To meet the inclusion criteria of 60 cases of acute bronchial asthma frigiopyretic asthma patients were randomly divided into two groups,treatment group and control group cases.The control group use western medicine treatment:mild patients:doxofylline 2 times a day,each time 0.2g.The moderate patients:inhalation of ipratropium bromide 2.5ml combined with budesonide suspension 2ml,2 times a day.The treatment group:oral Jiawei Houpu Mahuang Decoction(traditional Chinese medicine formula granules,a daily dose of morning and evening service).Both patients in the control group and treatment group were prepared with one Salbutamol Aerosol for needing.The course of treatment was 7 days.The clinical symptoms,pulmonary function and FeNO were observed after treatment.Result:1.There was no significant difference between the two groups before treatment(P>0.05).2.TCM syndrome curative effect:The total effective rate of the treatment group was 96.7%,the total effective rate of the control group was 90%,and the total effective rate of the treatment group was higher than that of the control group.There was no significant difference in total effective rate between the two groups(P>0.05).There was no significant difference between two groups of mild and moderate patients(P>0.05).3.The total score of clinical symptoms:Two groups of patients before and after treatment between groups,the difference was not statistically significant(P>0.05);after treatment was significantly lower than that before treatment(P<0.01);compare the difference before and after treatment,the difference was statistically significant(P<0.05).There was no significant difference between the two groups before and after treatment(P>0.05).The difference between the two groups of patients before and after treatment,the difference was statistically significant(P<0.05).4.Single symptom score:Two groups of patients before treatment between the two groups,there were no significant differences(P>0.05),after treatment was significantly lower than that before treatment(P<0.01);in coughing,wheezing,wheezing,chest tightness,compare the difference before and after treatment between the two groups after the treatment,the difference was not statistically significant(P>0.05),but in the aspect of sputum treatment after the difference between groups was statistically significant(P<0.05),the treatment group before and after treatment the difference was greater than the control group(P<0.05).There was no significant difference between the two groups before and after treatment(P>0.05).Two groups of patients with moderate wheezing,wheeze,cough,expectoration,compare the difference before and after treatment,there was no statistically significant difference(P>0.05),in the chest,after treatment in the treatment group than the control group the difference was statistically significant(P<0.05).5.Pulmonary function:Comparison of the main indexes of two groups of pulmonary function in patients with FEVi/FVC%and FEVi before and after treatment were compared between groups,the difference was not statistically significant(P>0.05);after treatment than before treatment significantly increased(P<0.01);compare the difference before and after treatment,the difference was not statistically significant(P>0.05).There was no significant difference between the two groups in the treatment of mild and moderate pulmonary function before and after treatment(P>0.05).6.FeNO:FeNO were compared between the two groups,before and after treatment were compared between groups,the difference was not statistically significant(P>0.05);after treatment were significantly lower than those before treatment(P<0.01);compare the difference before and after treatment,the difference was not statistically significant(P>0.05).There was no significant difference between the two groups in mild and moderate FeNO before and after treatment(P>0.05).7.Salbutamol use:The use of salbutamol in the total number of patients in the two groups were compared,the difference was not statistically significant(P>0.05).There was no significant difference between two groups of mild and moderate patients in the total number of salbutamol(P>0.05).Conclusion:Jiawei Houpu Mahuang Decoction has a good clinical effect on the patients of acute exacerbation of asthma with frigiopyretic asthma,can improve the clinical symptoms,improve lung function and reduce the FeNO value,and the curative effect is similar to that of the western medicine group.