| Objective:Learn Second Hospital of Tianjin Medical University hospital diagnostic cardiology since January 2008 to December 2012 period for the clinical data of patients with paroxysmal atrial fibrillation, atrial fibrillation follow-up patient outcomes, analyze the risk factors and prognostic impact, To investigate the clinical characteristics of the different risk factors for atrial fibrillation merger analyzes the status quo of AF treatment strategies.Method:Single-center retrospective case study method to collect the Second Hospital of Tianjin Medical University hospital diagnostic cardiology since January 2008 to December 2012 period as paroxysmal atrial fibrillation(parox ysmal AF) clinical data, detailed records of patients basic clinical characteristics, comorbidities, echocardiography during admission and the laboratory test results, treatment, follow-up of patients with atrial fibrillation outcomes. Respectively, according to sex, age, heart function, blood pressure, coronary heart disease, cerebral infarction, hyperthyroidism, left atrial diameter, left ventricular diameter, ejection fraction, history of smoking, drinking history, BNP, CRP, BMI and treatment strategies comparative analysis of paroxysmal atrial fibrillation group to permanent atrial fibrillation is characterized by further analysis of paroxysmal to permanent atrial fibrillation in patients with risk factors, prognosis and treatment strategies.Result:(1). The study enrolled a total of 524 cases of paroxysmal atrial fibrillation patients, aged 26-93 years old(70.8 ± 11.4 years), 246 cases of male patients, female patients with 278 cases, a total of 166 cases of paroxysmal to permanent atrial fibrillation atrial fibrillation, the conversion rate was 31.7%.(2) grouped by gender, the prevalence of paroxysmal atrial fibrillation with no significant gender-related.(3). unconverted compare clinical data and laboratory results between the group and the conversion group found that age, BNP, LAD, LVED, LVEF, cerebral infarction, cardiac function levels between the two groups was statistically significant(P <0.05). Conversion age group 77.0 years(71.0 82.0) compared with 70.0 years old unconverted group(60.0 77.3) is significantly higher, BNP index conversion group 476.0pg / ml(309.8 927.0) compared with an unconverted group 189.0pg / ml(135.0315.0) was significantly up high, LAD index value conversion group 45.9mm(43.6 49.9) compared with unconverted group 40.4mm(38.0 43.4) was significantly higher, LVED index value conversion group 58.5mm(55.0 60.5) compared with unconverted group 54.8mm(50.5 57.5) was significantly up high, LVEF values converted group 49.0%(44.0 54.3) compared with 58.5% unconverted group(53.0 65.0) significantly reduced the degree of conversion group heart function was significantly lower than the unconverted, suffering from cerebral infarction scale conversion group(66 cases 39.8%) compared with unconverted group(67 cases 18.7%) was significantly increased.(4). Convert group and treatment strategies unconverted comparison group taking digoxin, ?-blockers ratio between the two groups was statistically significant(P <0.05). Oral ?-blockers proportion unconverted group(198 cases 55.3%) compared with the conversion group(44 cases 26.5%) significantly increased the proportion of conversion taking digoxin group(115 cases 69.3%) compared with unconverted group(85 cases 23.7 %) significantly increased the proportion of unconverted oral amiodarone group(58 cases 16.2%) compared with the conversion group(14 cases 8.4%) increased significantly.(5). The risk factors for atrial fibrillation and paroxysmal to permanent AF-related logistic regression analysis, the final draw for senior citizens, LAD increases, LVEF decreased cardiac dysfunction, oral digoxin is the turn of paroxysmal atrial fibrillation permanent atrial fibrillation risk factors(P <0.05).(6). Most of paroxysmal atrial fibrillation to permanent conversion time occurred in the first five months in patients with paroxysmal atrial fibrillation in patients between 20 months.(7). The current treatment of paroxysmal atrial fibrillation digoxin level oral ?-blockers accounted for the majority, followed by amiodarone.Conclusions:paroxysmal atrial fibrillation to permanent atrial fibrillation in patients with no significant gender differences.Elderly, LAD increases, LVEF lower, BNP increased heart dysfunction, oral digoxin is an independent risk factor for paroxysmal to permanent atrial fibrillation. patients with permanent atrial fibrillation stroke risk was significantly higher than that in patients with paroxysmal atrial fibrillation and other epidemiological characteristics similar to those reported in literature. It is recommended as treatment for patients with paroxysmal satisfied with digoxin, amiodarone as far as possible, according to the findings, such as radiofrequency ablation. |
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