| Objective:To investigate the prevalence and epidemiologic characteristics of impaired glucose metabolism and metabolic syndrome of the in-service army cadres stationed in Fujian, and to explore its internal relationship between the related risk factors and forecast the trend of mpaired glucose metabolism and metabolic syndrome, which is also to provide basic data for drafting and evaluating the health policies and interventional measures.Methods:Randomly selected adults were studied by means of multi-stage sampling. A cross-sectional study was conducted in a in-service cadres crowed in Fujian with a representative sample of 958 Chinese adults.Each participant was carried on the questionnaire survey. After an overnight fasting, participants underwent an oral glucose tolerance test, fasting,0.5-hour and 2-hour plasma glucose and insulin, blood lipid profile, hemoglobin A1 c, urine trace albumin/creatinine ratio as well as height,body weight, blood pressure were measured. To understand the prevalence of impaired glucose metabolism and metabolic syndrome and the related risk factors.Results:1. The prevalence of diabetes and prediabetes were 1.67%(1.66% for men and 1.77% for women) and 9.71%(10.18% for men and 5.31% for women) respectively, so the prevalence of impaired glucose metabolism was 11.38%(11.84% for men, 7.08% for women). And the prevalence of metabolic syndrome was 11.9%(12.54% for men and 7.08% for women). Between different genders all the prevalence were no statistically significant difference(P>0.05).2. The prevalence of diabetes, prediabetes and metabolic syndrome increased with increasing age, and increased rapidly after age 45.3. Between combat troops and noncombat troops, the prevalence of impaired glucose metabolism was no statistically significant difference, while the prevalence of metabolic syndrome combat troops was lower than that of the noncombat troops(9.48% vs 13.64%,P<0.05).4. Between sleep deprivation, adequate sleep and long sleep, the prevalence of IGR were 10.69%,8.45% and 12.50%, the prevalence of DM were 1.91%,1.17% and 12.50%, the prevalence of MS were 11.45%,11.27% and 0.00%, respectively, and in which adequate sleep had the lowest prevalence.5. The IGR rate of low weight, normal weight, overweight and fat people were 0.00%, 5.95%, 13.21% and 18.57%, respectively. The DM rates were 0.00%, 0.82%, 2.33% and 4.29%, respectively. The prevalence of central obesity and normal person were 17.59% and 7.64%, and the DM rates were 4.52% and 0.92%, respectively.6. Between high SBP and normal person, the prevalence of IGR were 22.58% and 8.32%, the prevalence of DM were 6.45% and 1.16%;And between high DBP and normal person, the prevalence of IGR were 16.06% and 8.65%, the prevalence of DM were 5.11% and 1.10%.7. The IGR rate of high total triglyceridemia and normal person were 31.25% and 7.31%, the prevalence of DM were 4.17% and 1.39%.8. Relative factors of impaired glucose metabolism included: aging, high systolic blood pressure, BMI,high waist and high total triglyceridemia. The high-density lipoproteincholesteol was the protective factor.9. In the combination of metabolic syndrome, the merge five components of metabolic abnormalities accounted for 7.89%, the combining four components account for 25.44%, the merge three components accounted for 66.67%. The most common combination of three components in MS was central obesity, high triglyceridemia and hypertension.10. The MS rate of smokers and non-smokers were 18.40% and 9.10%. And between drinkers and non-drinkers, the prevalence of MS were 17.77% and 7.8%.11. Between diabetic family history and non-diabetic family history, the prevalence of MS were 22.39% and 10.19%. Between hypertension family history and non-hypertension family history, the prevalence of MS were 17.84% and 9.9%. And between hyperlipidemia family history and non-hyperlipidemia family history, the prevalence of MS were 25.69% and 10.13%.12. In the normal glucose people, the MS was higher than non-MS in FPG, PG(0.5h), PG(2h), HOMA-IR, HOMA-? and ?I30/?G30, the DI1 and DI2 were lower than non-MS.13. The aging, history of smoking, drinking, family history of hyperlipidemia, sleep deprivation and HOMA-IR were independent risk factors of MS, the regular exercise and DI2 were the protective factors.14. Linear correlation analysis showed that BMI, waist circumference and waist-hip ratio respectively have a positive correlation between HOMA-IR ?HOMA-???I30/?G30?Hb A1 c, and have negative correlation with DI1, and with the correlation of DI2 had no statistically significant difference. Sleep deprivation and BMI, waist circumference, waist-hip ratio were positively correlated.Conclusion:1.The prevalence of impaired glucose metabolism and the metabolic syndrome in the forces' in-service cadres in Fujian are lower than the national average level, also below the average level of Fujian province. The prevalence of metabolic syndrome of combat troops was lower than that of the noncombat troops.2. It had existed insulin resistance and ?-cell function disorder in the impaired glucose regulation stage of abnormal glucose metabolic people, and with a variety of metabolic abnormalities, which is the high risk population of cardiovascular disease. The aging, high systolic blood pressure, BMI,waist and high total triglyceridemia were independent risk factors of impaired glucose metabolism, the high-density lipoproteincholesteol was the protective factor.3.For persons over age 50, or with high TG levels and high SBP in the physical objects should be normal to undergo an OGTT test, in order to make clear whether the glucose metabolism abnormalities.4 It had existed insulin resistance and ?-cell function disorder in the MS of normal glucose metabolic people. The aging, history of smoking, drinking, family history of hyperlipidemia, sleep deprivation,Hb A1 c and HOMA-IR were independent risk factors of MS, the regular exercise and DI2 were the protective factors. The correlation of metabolic syndrome with waist circumference is better than with body mass index and waist-hip ratio, so that the IDF criteria can check out the people in advance.5. OGTT test is more sensitive to accurately reflect the severity of impaired glucose metabolism and metabolic syndrome, so it is important to undergo an oral glucose tolerance in the patients with metabolic syndrome. |
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