| Objective: This topic using randomized controlled methods,as heart and kidney do not pay type insomnia patients TCM symptom score,Pittsburgh sleep quality index and guide polysomnography monitoring data were used as indicators to evaluate Anshen Decoction in the treatment of heart and kidney do not pay the clinical efficacy and safety of insomnia,for the treatment of heart and kidney do not pay type insomnia provides new ideas,and to guide clinical practice.Methods: According to the random number table method will meet the inclusion criteria of 72 patients with heart and kidney do not pay type insomnia patients were randomly divided into treatment group and control group,with 36 cases in each,treatment group oral Anshen Decoction,control group was treated with right zopiclone tablets,4 weeks of treatment,TCM syndrome score changes was observed after the end,Pittsburgh sleep quality index score changes,and through polysomnography,observed before and after treatment of two groups of patients with total sleep time,sleep latency time,awakening times and non rapid eye movement sleep stage time changes to evaluate the efficacy and safety,after 1 weeks of withdrawal,two groups of patients were followed up to observe the recurrence of insomnia in two groups.Results: Clinical total 72 cases(36 cases in the treatment group,1 cases in the treatment group,36 cases in the control group and 1 cases in the control group),the age and gender were compared before treatment,the two groups were comparable(P > 0.05).1.The total effective rate of the treatment group was 85.87%,the control group was88.57%,the total effective rate between the two groups was not statistically significant(P >0.05).2.Two groups of patients with traditional Chinese medicine syndrome score than before treatment were improved(P < 0.05),the treatment group than the control group(P < 0.05).3.The PSQI scores of Two groups were lower than before treatment(P < 0.05).There was no significant difference in PSQI scores between the two groups(P > 0.05).4.Two groups of patients with multichannel sleep instrument monitoring indicators(total sleep time,sleep latency time,awakening and the number of non rapid eye movement sleeptime)compared with those before treatment were improved(P < 0.05),between the two groups of each index compared statistically significant(P > 0.05).5.1 week withdrawal after follow-up,patients in the treatment group PSQI score and the treatment after,the difference was not statistically significant(P > 0.05),but the control group of PSQI treatment increased(P < 0.05)withdrawal after 1 week of PSQI scores of the two groups compared with that in the treatment group than in control group(P < 0.05).Conclusion: Anshen Decoction in the treatment of heart and kidney do not pay type insomnia and eszopiclone efficacy similar,but in improving TCM syndrome is superior to eszopiclone,and no dependence and significant side effects,safe and effective. |
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