The Research For Incidence And Related Factors Of Macrosomia In Suzhou

[Objective] To investigate the incidence of macrosomia from 2014 in Suzhou, Anhui province, analysis and explore the related factors of macrosomia. This paper provides a scientific basis for establishing prevention and healthcare strategies and measures of maternal and child, to reduce the incidence of high birth weight in the area, ensure maternal and child's safety and improve population quality.[Method] The statistic data of macrosomia incidence has been acquired from regional health information platform- �Suzhou maternal and child health information system�. The paper uses case-control methodto gain analysis data for the related factors of macrosomia, selects 299 macrosomia cases as observation group, which has been born from Oct. 1st, 2013 to Jun.1st, 2014 in Suzhou. Meanwhile, it selects 300 cases of normal birth weight as control group born in the same period. By consulting medical history, it has got details about mothers during pregnancy and newborn, which include maternal general situation, such as age, production time, gestational age, etc., pregnancy complications like GDM, etc., perinatal outcome like delivery way, and the newborn general situation,such as birth weight, gender, presence of neonatal asphyxia, etc. By SPSS 19.0 statistics software to analysis, it used t test or c2 test to filter independent variable by single factor analysis, and the independent variable that has a significant meaning carried out a multi-factor unconditioned Logistic regression analysis, selected risk factors by stepwise regression brought into the equationand calculatedthe OR and 95% confidence interval, P < 0.05 has statistical difference.'[Result] During 2014(from Oct. 1st, 2013 to Sept. 30 th, 2014), in Suzhou, there was 86178 cases newborn, including 5320 cases of macrosomia, and the macrosomia incidence was 6.17% in the area. Birth weight of macrosomia group is 4265.26 g � 268.42 g,and the control group is 3376.52�423.71 g, the difference had statistical significance(P< 0.05). Macrosomia group has 187 cases male infant(62.5%), 112 cases female(37.5%), two groups of gender had significant statistical differences(P< 0.05). Conpare with these groups of maternal situation, it has statistical differences in pregnancy times, delivery times, pregnant age, gestational diabetes mellitus(GDM), the way of delivery and gestational age, ect. The paper makes all of meaningful factors that were uesd by single factor analysis as independent variable, and adopts multi-factor unconditioned Logistic regression analysis. It has confirmed six fators as macrosomia related factors. Firstly, the highest OR weight during pregnancy,(OR = 6.145), the highest influence degree. Secondly, it is pregnancy BMI(kg/m2)(OR = 3.774). Thirdly, it is the gestational diabetes(OR = 1.607). Meanwhile, the male newborns, delivery mode and pregnant times also can increase the incidence of macrosomia probably.[Conclusions]I. The incidence of macrosomia in 2014 was 6.17% in Suzhou, Anhui province, which is lower than the national leve, 7.3%, and lower than the 10.6% in developed economic regions ofnhui province. The reason for this may be related to living standards, pregnant women's nutrition and diet in Suzhou, located in Wanbei economic under-development areas. II. The result shows that the dangerous factors of macrosomia including pre-pregnancy body mass index(BMI) ?24.0, pregnancy weight gained?16 kg, gestational diabetes mellitus(GDM), times of pregnancy?2 times, delivery times?2 times, gestational age?40 weeks, and Male infant. It is the same results between domestic and abroad. III. Considering the macrosomia prevention, it should make the key intervene factors like controlling BMI during pre-pregnancy and pregnancy, reducing the incidence of gestational diabetes mellitus(GDM), and controlling gestational age, ect., and should be taken as a key point of macrosomia in prevention. IV. According to the result, it should strengthen pre-pregnancy education, control pregnancy weight to ready for scientific parenting, and strengthen the guidance during pregnancy, control weight during pregnancy, appropriate exercise, and balanced diet to reduce the risk of macrosomia.