| It is known that ?-hydroxy-?-methyl-butyrate (HMB) is a new functional additives,which can improve the reproductive performance of sows. However, data is lacking for dose-response effect of HMB supplementation on performance of sows in perinatal period. So, this study was conducted to investigate the effects of dietary different levels of HMB supplementation in perinatal period on productive performance, plasma biochemistry in sows and her piglets. Total of 120 3-6 parity sows(PIC) were randomly divided into 4 groups,30 sows each group:0.00% HMB, 0.10% HMB,0.20% HMB,0.30% HMB, depending on them backfat (20.90± 3.16mm). Sows in the 0.00% group were fed a basal lactation diet, and the others were fed the basal diets supplemented with 0.10%,0.20%,and 0.30%?-hydroxy-?-methyl-butyrate calcium (HMB-Ca), respectively. Treatment began 2 weeks before farrowing, ending with first week of lactation.The experiment lasted from 2 weeks before farrowing to weaning. The result indicated that:There was no difference with the number of total and live-born piglets, birth weight of live-born piglets and rate of stillbirth (P>0.05).Otherwise,0.20% HMB group had a higher litter birth weight (P<0.05) and a lower rate of IUGR in newborn piglets. The born splayleg rate of new born piglets were linearly decreased across increasing supplementation of sows' diet with HMB (R2= 0.903,P<0.01).In first week of lactation,0.20% HMB group improved piglets body weight, litter weight and ADG. There was significant quadraticly relationship between litter weight with supplementation levels (R2= 0.642), and the optimal level of HMB for litter weight was 0.22% in first week. At weaning,0.30% HMB group improved piglets body weight, litter weight and ADG. There was significant quadraticly relationship between litter weight with supplementation levels (R2= 0.988), and the optimal level of HMB for body weight was 0.29% on weaning. At whole lactation period, the sows ADFI of 0.30%HMB group was more than 0.00% and 0.10% HMB groups (P<0.05). In first week of lactation period, sows fed 0.20% HMB group lost more backfat than other groups (P<0.05), the other phases had no difference (P> 0.05).On parturition, fat content of colostrum was significantly negative correlation with supplementation of sows' diet with HMB (R2=0.914, P<0.01). Meanwhile, in day 7 and 21 of lactation, there was significant quadraticly relationship between milk fat content with supplementation levels (R12= 0.999, P<0.05; R22=0.995,P<0.05), when adding levels reached 0.19% and 0.24% milk fat content achieve the top, respectively.In delivery, plasma PUN concentrtion was significant quadraticly with adding level (R2= 0.753, P<0.05), when HMB added 0.16% plasma PUN concentration reached the bottom, the plasma TG concentrtion were linearly decreased across increasing supplementation of sows diet with HMB (R2=0.691, P<0.01). On day 7 of lactation, there was significant quadraticly relationship between plasma PUN,TC concentration with the levels of dietary HMB (R2=0.783,P<0.01; R2=0.989, P< 0.05). Meanwhile, the plasma GLU concentrtion was linearly decreased across increasing supplementation of sows' diet with HMB (R2= 0.670, P<0.01). On day 7 of lactation, the plasma PUN concentration with supplemental levels were significant-ly correlated (R2=0.777,P<0.01).On the day 7 of lactation, piglets from 0.20%HMB group had a significantly higher plasma IGF-1 concentration than 0.00%HMB group (P<0.05).On weaning day, piglets from 0.30%HMB group had a higher plasma IGF-1 concentration than0.00%HMB group (P<0.05). On parturition, piglets from 0.30%HMB group had a lower plasma IGF-2 concentration than 0.10% and 0.20%HMB groups (P<0.05).On delivery, compared with 0.00%HMB group, sows in 0.20% had a lower plasma valine and isoleucine concentration (P<0.05), but had a higher plasma proline and ornithine concentration (P<0.05). In newborn piglets, plasma amino acid concentration linearly increased across increasing supplementation of sows diet with HMB.In conclusion:In our experiment, sows fed a supplemental 0.20% HMB diet improved sow biochemical marker, milk yield and milk fat content, reduced the rate of IUGR, had a better piglets weight in 7 and 21 day on lactation, and a higher average daily gain. |
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