The Relationship Between Portal Venous Thrombosis And Abnormal Coagulation Function In The Decompensated Cirrhosis

Objective:To explore the relationship between portal venous thrombosis(PVT) and abnormal coagulation function in the decompensated cirrhosis.Methods:131patients with the decompensated cirrhosis were involved in this study,including 21 with PVT as PVT group and 110 without PVT as none-PVT group.Age,gender,etiology,PT,APTT,INR and Fib were recorded and analyzed. The measurement data were analyzed by t test.Area under curve(AUC)was calculated according to receiver operator characteristic(ROC)curve to evaluate the diagnostic value of each index.Results:Compared with none-PVT group,the PT、INR、APTT of PVT group are lower but its Fib is higher(P<0.05).There are no significant statistical differences among the age,gender,etiology between the two groups with P>0.05.The predicted values resulting from AUC under the ROC curve are as follow:Fib(0.768)>APTT(0.273)>INR(0.209)>PT(0.196).Conclusion:The higher Fib and relative hypercoagulability are risk factors for PVT in the patients with the decompensated cirrhosis.