MSCT Features Of Small Cell Lung Cancer

Objective: Improve the diagnosis of small cell lung cancer by comparing the analyzing of small cell lung cancer and squamous cell carcinomas characteristics of MSCT and pathological basis.Methods: Collecting 2012.6—2015.7 Our hospital diagnosis and treatment of lung cancer patients, and have a complete CT and clinical data of proved pathologically 47 cases(24 cases small cell lung cancer, 23 cases central type Lung squamous carcinoma), observing its chest MSCT features, and combining with other clinical data to summarize and analyze the CT image features of SCLC.Results: Small cell lung cancer presented as central lung cancer in 23 patients, while as peripheral lung cancer in 1 cases; CT manifestation hilus of the lung lobulation nodule or masses, among 24 cases small cell lung cancer, there were 6 cases with homogeneous density, 15 cases with necrosis, 11 cases with calcification, 12 cases with bronchial constriction, 11 cases with bronchus truncation sign, 11 cases with obstructive pneumonia or atelectasis; 22 cases with mediastinal lymphadenectasis,14 cases with merging of lymph nodes.13 cases with merging of mass and lymph nodes,12 cases with frozen mediastinum;14 cases had distant viscera metastasis,11 cases of contrast-enhanced CT scan, the tumor and enlarged lymph nodes that displaying slight heterogeneous enhancement in enhanced scan. Peripheral small cell lung cancer in 1 case,CT manifestation peripheral lobulation tumor,with edge smooth and homogeneous density. Squamous cell carcinoma as central lung cancer in 23 patients; CT manifestation hilus of the lung irregular nodule or masses, among 23 cases small cell lung cancer, there were 11 cases with homogeneous density, 8cases with necrosis, 9cases with calcification, 18 cases with bronchial constriction, 7cases with bronchus truncation sign, 21 cases with obstructive pneumonia or atelectasis; 15 cases with mediastinal lymphadenectasis;1 cases had distant viscera metastasis. Carcinomas between the central type of small cell lung cancer and central type squamous cell carcinoma : the central type of small cell lung cancer located at the left upper lobe, focus smooth edge, vascular convergence sign, pulmonary artery and branches invasion, pulmonary vein and branches invasion appeared higher in central type of small cell lung cancer, a statistically significant difference(P<0.05). Mediastinal lymphadenectasis, merging of lymph nodes, merging of mass and lymph nodes, frozen mediastinum appeared higher in central type of small cell lung cancer, a statistically significant difference(P<0.05). Oesophagus invasion, pleural effusion, distant metastasis appeared higher than central type of small cell lung cancer, a statistically significant difference(P<0.05). Spinous process signs, speculation, cuplike bronchial stenosis, bronchial intraluminal nodules appeared higher in central type squamous cell carcinoma, a statistically significant difference(P<0.05). Obstructive pneumonia or atelectasis appeared higher in central type squamous cell carcinoma, a statistically significant difference(P<0.05).Conclusion: CT manifestation of SCLC showed the central type cancer of lung predominantly, the tumor has homogeneous density with hilar, and frequent stenosis of bronchus, easily invaded to large vessels of mediastinum; and more with hilar and mediastinal lymph node metastasis, forming the "frozen mediastinal", proning tco distant metastasis easily.The tumor has homogeneous density with hilar, frozen mediastinum and large vessels of mediastinum invasion may be the specific CT features of small cell lung cancer.