| Objective: By collecting the clinical data of 52 patients with epilepsy after cerebral infarction of department of neurology in Shanxi People’s Hospital, follow up the seizures situation, to analysis risk factors of epilepsy after cerebral infarction, investigate the risk for recurrence of epilepsy, to improve the prognosis of patients.Methods: A case-control study was used in this study. 52 patients with epilepsy after ischemic stroke from 2014 to 2015 in Shanxi People’s Hospital were chosen as case group, and no patients with epilepsy after cerebral infarction of 60 patients in the control group, the data of two groups were collected for analyzing the risk factors of epilepsy after ischemic stroke, such us age, gender, drink, history of hypertension and diabetes and hyperlipoidemia, types of cerebral infarction, infarct location, infarct size, cerebral blood supply system, NIHSS scores, cerebral infarction complications(pulmonary infection), electroencephalogram, the risk factors of ischemic stroke epilepsy were analyzed with the help of Logistic Regression Model.Results: 1. The total number of patients with epilepsy after cerebral infarction in this group were 52 cases, male 30 cases, female 22 cases; 2. Univariate Logistic regression analysis showed that type of cerebral infarction, infarct location, infarct size, Cerebral blood supply system, NIHSS scores have difference statistically between two groups(P<0.05); 3. The multivariate analysis shows there are 4 risk factors into the final model, they are infarct location, infarct size, Cerebral blood supply system and NIHSS scores(P<0.05); 4. In epilepsy group, there are 19 early-onset seizures cases and 33 late-onset seizures cases, seizure time in the NIHSS score group, the difference of the lesion area group was not statistically significant(P>0.05), there was significant difference in the lesion location group(P<0.05); 5. 34 cases presented with partial seizure and 8 cases with generalized seizure and 10 cases presented with partial seizures secondary to total seizures in this study, there were no difference statistically between infarct location and infarct size(P>0.05), there was a significant difference between the three groups in the attack time of epilepsy(P<0.05), comparison of any two groups, there was a statistical significance between the two groups in the partial seizures and the comprehensive attack(P<0.0125), there was no statistical difference between the partial seizures and partial seizures secondary to a comprehensive attack group, partial seizures secondary to total seizures and the comprehensive attack group(P>0.0125); 6.EEG of interictal stage in 52 patients, the abnormal rate of EEG was 79%, 26 of them can be captured in epileptic-form discharges which were consistent with lesion sites;Conclusions: 1. cortical location, large area cerebral infarction, high NIHSS scores(>15scores), involving Anterior circulation system are the independent risk factors of post ischemic stroke epilepsy. 2. The case of late-onset seizures in post ischemic stroke epilepsy arc more than early-onset seizures. Early-onset epilepsy was more common in cortical lesions, and delayed epilepsy was more common in subcortical lesions. 3. The most common form of epilepsy after ischemic stroke are partial seizures, followed by partial seizures secondary to a comprehensive attack, a comprehensive attack rare. Comprehensive seizures caused by early onset epilepsy, partial seizures caused by delayed epilepsy. 4. EEG diagnosis is an essential means of checking on post ischemic stroke epilepsy,In this study, the EEG of epilepsy after cerebral infarction was moderately abnormal, and the abnormal rate was 79%. 50%of patients can be captured in epileptic-form discharges which were mainly seen in the cortical location. lesion close to the cortex have high positive rate which were consistent with lesion sites. |
