Based On Data Mining Technology Of Treating The Recurrent Abortion Syndrome Treated By Professor Song-ping Luo Retrospective Study

ObjectiveThis research through the inheritance of traditional Chinese medicine auxiliary platform of data mining technology, professor song-ping luo treatment of recurrent abortion patients were retrospectively analyzed the drug laws and explore the new process of combination. In summary by large sample statistics ROM teacher in RSA patients diagnosis and treatment and medication rule, to inherit and carry forward its academic thought, thus further guide clinical TCM physician of department of gynaecology, give full play to the advantages of TCM gynecology in the fetus and characteristics.MethodsFocus on data mining technology, this study will be ROM division since 20132016 outpatient service of department of gynaecology the clinical basis for the treatment of recurrent miscarriage retrospective study, divided into two periods after pregnancy and pregnancy. By collecting clinical cases, sorting as basis materials, to extract its history, the four diagnostic information, diagnosis, syndrome and prescription drugs, traditional Chinese and western medicine into the Excel spreadsheet, unified data cleaning, after double check (back to back) the manual entry to the inheritance of traditional Chinese medicine auxiliary platform system (V2.5), using its "prescription analysis" and "basis analysis module of frequency analysis, correlation analysis, cluster analysis method of statistics, in combination with ROM division and published in the outpatient service clinical teaching academic experience, to summarize the diagnosis and treatment law and analysis.ResultsThis study included in the standard case information collected a total of 300, a total of 3305 prescriptions, including prescription 2209 zhang before childbirth, pregnant after prescription 1096 zhang. According to the statistics after mining technology, specific results are as follows: 1, in cases of basic information:this included in the study of 300 patient records, the average age of 30.55 years, minimum of 24 years old, biggest 41. The minimum number of abortions for 2 times, the highest up to 6 times. 2, the syndrome distribution characteristics:in this study the prescription can be divided into two times after pregnancy and pregnancy, further divided into deficiency syndrome, empirical, factors, analysis:luo division in two times the dialectical into virtual license, deficiency syndrome before and after pregnancy stages in spleen and kidney is not solid type lead to; Empirical person’s pregnancy respectively for the blood stasis syndrome, pregnancy after liver stomach don’t; Pregnancy factors shall be considered as change the certificate, after pregnancy to wet pixu (spleen deficient) certificate.3. The clinical medication rule mining analysis:3.1 the frequency analysis of Chinese traditional medicine after pregnancy and pregnancy:regulate the prescription 2209 zhang before childbirth, a total of 141 kinds of traditional Chinese medicine (TCM), the fetus during pregnancy treatment prescription,1096,108 and taste traditional Chinese medicine (TCM). Pregnancy regulate the highest frequency of use of the top 10 of dodder (7.71%), Chinese yam, respectively (6.95%), fracture (6.16%), the mulberry parasitism (6.13%), atractylodes (5.46%), codonopsis (4.67%), raspberries (3.80%), caulis spatholobi (3.71%), the root of remembranous milk vetch (3.56%), fructus ligustri lucidi (3.48%). When pregnant fetus medicines for top 10 flavour of dodder (8.34%), radix dipsaci, respectively (8.32%), mulberry parasitism (8.32%), yam (8.25%), codonopsis (6.26%), atractylodes (6.26%), dried tangerine or orange peel (5.97%), raspberries (5.39%), fructus rosae laevigatae astragalus membranaceus (4.50%), (2.94%).3.2 effectiveness classification analysis:in this study,3305 prescriptions of traditional Chinese medicine (TCM) after pregnancy and pregnancy are summarized as 20 classes, pregnancy stages, respectively is: the top five heat-clearing and medicine, and qi, promoting blood circulation to remove blood stasis drugs, Yang, Yin tonic medicine; After pregnancy stage with spleen medicine, heat drugs, tonifying qi medicine, ranks the five Yang, Yin tonic medicine, but in terms of its using frequency statistics, both to make up for virtual medicine is given priority to, in the first place is mend angry medicine.3.3 drug four, five, owned by the analysis:whether before or after pregnancy, the top three of the drug for liver, spleen and kidney but pregnancy drugs into the liver meridian in the first place, after pregnancy to belong to the kidney by the drug in the first place. After pregnancy and pregnancy, are all on the four gas temperature, cold, the top three. As you can see medicine mixed analysis after pregnancy, pregnancy is sweet, bitter, bitter taste drugs. Overall medicinal properties is relatively peaceful, give priority to with sweet, bitter, warm, smooth, give priority to with removing. Formula regularity of formula based on association rules analysis:3.4 the association rule analysis of this study support by setting before and after pregnancy prescription number 1105 and 548 respectively (support degree 50%), the confidence level is 0.9, statistical analysis:pregnancy stage often use drug combinations are:codonopsis, mulberry parasitism, radix dipsaci; Mulberry parasitism, raspberry, radix dipsaci; The dodder weed, dangshen, mulberry parasitism, radix dipsaci, etc. After the pregnancy stages often use drug combinations are:the dodder weed, radix dipsaci; The dodder weed, mulberry parasitism; Radix dipsaci, mulberry parasitism, and so on. Can be seen on the benefit spleen kidney ROM teacher major for commonly used drugs in the square life of fetal pill and sijunzi decoction on the basis of add and subtract the cutting.3.5 based on improved mutual information method and formula of entropy clustering analysis of New Zealand:New Zealand analysis specific mining results of this study are as follows:pregnancy stage explore medication combined with radix dipsaci, suberect spatholobus stem; Dangshen, mulberry parasitism, suberect spatholobus stem; Radix dipsaci, radix bupleuri, etc. One party is given priority to with nourishing liver and kidney, and the other one party or invigorate the circulation of blood, or liver resolve depression, manifests the ROM teacher both when in view of the pregnancy stages, the characteristics of the attack and supplement. After pregnancy stage drug combination with dangshen, caulis dendrobii; Astragalus root and caulis dendrobii; Radix paeoniae alba, rhizoma atractylodis, etc. Embodies the ROM t stage during pregnancy in solid to protect the spleen and kidney function at the same time, give priority to with clear heat, to prevent thermal perturbation tire yuan. By correlation is set to 8, punishment degree is set to 2, can be concluded that core group division in the treatment of recurrent abortion of a total of 14, there are 7 first, come to New Zealand by further clustering rehmannia glutinosa_ suberect spatholobus stem_ raspberry salvia miltiorrhiza respectively; Orange nuclear_ rhizoma zedoariae triangular_ turtle shell; Atractylodes_ rhizoma atractylodis_ dolichos lablab 1._ plantain; Rhizoma ligustici wallichii_ honeylocust thorn_ dodder_; Radix dipsaci_ _ mulberry parasitism_ astragalus codonopsis pilosula_ rehmannia glutinosa_ angelica; Radix dipsaci_ mulberry parasitism angelica raspberry_ yam_ rehmannia glutinosa_ medicinal indianmulberry root; Radix paeoniae alba_ _ _ astragalus codonopsis pilosula medlar_ the_ fructus ligustri lucidi limit; After pregnancy drugs of clustering analysis of New Zealand, core combined with 6to New Zealand first, a total of 3 respectively: Gordon euryale_ wine cornus_ the_ limit eucommia bark; Raspberry of eucommia ulmoides licorice_ _ _ gelatin beads; Bone skin_ in radix paeoniae alba_caulis dendrobii_ _ _astragalus codonopsis pilosula; Amomum villosum_ gelatin_ bergamot_ purple Perilla.ConelusionThis study retrospectively 300 cases of professor luo treatment for recurrent abortion clinic medical record to carry on the data mining, through the research on the laws of the certificate for analysis.1. Professor song-ping luo is lingnan roche descendants of department of gynaecology genre. For the diagnosis and treatment of recurrent miscarriage, paying equal attention to both nature and nurture, pay attention to kidney and spleen, in order to restore "kidney-menstruation - ran ren - cell palace" reproductive axis function normal operation, to life of fetal pill and sijunzi decoction cutting add and subtract.2, from guangdong subtropical geographic features and the female, belt, tires and production, the physiological characteristics of mixed perspective, whether before or after pregnancy two stages are attaches great importance to the Yin "clear heat, moment protect women Yin points. In the stage of pregnancy, cooperate with western medicine auxiliary examination results, emphasis on women and regulation of qi activity of using promoting blood circulation to remove blood stasis oscillation tuning stasis, both cellular palace; After pregnancy often cooperate with astringent medicine, have astringent solid tire.3, professor luo each prescription of TCM clinical application frequency is generally not more than 12 herbs, medicine gentle light spirit, specially pays attention to less force, as the change of illness constantly adjust drug use.