The Clinical Study Of Low Frequency Pulse Acupoint Stimulation On Diabetic Patients With Constipation

ObjectiveTo explore effect of low frequency pulse acupoint stimulation on diabetic patients with constipation, the changes of the first defecation time, the number of bowel sounds, plasma NO, symptom score and the effect of constipation were observed, Aiming to observe the curative effect and safety of low frequency pulse acupoint stimulation on diabetic patients with constipation, and to provide the basis for clinical application of low frequency pulse treatment for diabetic constipation.MethodWe select 74 patients who were diagnosed with diabetic constipation in Three Level of First-class Hospital from march 2015 to September 2015 for observing, According to the inclusion and exclusion criteria,74 patients were randomly divided into experimental group (37cases)and control group(37cases),All the patients received basic nurse and treatment and the routine treatment of constipation,while the experimental group received two weeks’ low frequency pulse acupoint stimulation once a day and 30 mintues per time based on the treatment of the control group, record the first defecation time, bowel sound frequency, plasma NO value, symptom score, Adverse reactions and recurrence of constipation after two weeks of follow-up before and after the treatment of the two groups.Results1. Baseline comparisonThere were no significant difference in the general situation(age, gender, course of disease, medication taken, blood glucose, glycosylated hemoglobin, etc)and the evaluation index baseline(The first defecation time, bowel sound frequency, plasma NO value, TCM symptom score)in the two groups before intervention(P>0.05),it showed that the two groups were comparable.2. The first defecation timeThe difference of the first defecation time between the two groups was statistically significant after two weeks of intervention(P<0.05).3. Bowel sound frequencyThe difference of the Bowel sound frequency between the two groups was statistically significant after two weeks of intervation(P<0.05).4. Plasma NO valueThe difference of the plasma NO value between the two groups was statistically significant after two weeks of intervention(P<0.05).5. Constipation symptom scoreAfter one week of intervention. The difference of each symptom scores in experimental group was statistically significant compared with the time before the experiment(P<0.05), while there was no significant difference in control group(P>0.05) expect stool characters.There was no significant difference in each symptom scores between the experimental group and the control group (P>0.05)expect defecation time and stool characters(P<0.05).After two weeks of intervention, The difference of each symptom scores in experimental group was statistically significant compared with the time before the experiment(P<0.05) and the same in the control group(P<0.05). The difference of each symptom scores between the experimental group and the control group was statistically significant (P<0.05),except the desire of defecate and the accompanying symptoms (P>0.05). The difference of the total score of constipation in the two groups was statistically significant(P<0.05).6. Clinical efficacy of constipationAfter two weeks of intervention, the total efficiency was85.29% in the experimental group,and 57.15% in the control group, the difference between the two groups was statistically significant(P<0.05).7. Adverse eventsAfter the intervention, the incidence of adverse reactions in the experimental group was 2.94%,which was lower than that of the control group (14.29%),and there was no significant difference between the two groups (P>0.05).8. The recurrence of constipationTwo weeks after the end of test, the number of constipation recurrence were 5 cases (17.24%) and 12 cases(60%), respectively, for the test group and the contro group, and the difference was statistically significant between the two groups(P<0.05).ConclusionLow frequency pulse acupoint stimulation can effectively improve the constipation syndrome of diabetic patients with constipation, and will not increase the incidence of adverse reactions in patients, and at the same time it has a long-term effect in some extend, Therefore, low frequency pulse acupoint stimulation is a simple and effective method to improve the effect of constipation in patients with diabetes.