Application Of Fiberoptic Ductoscopy For Nipple Discharge

Objective:To evaluate the clinical application of mammary ductoscopy in the diagnosis of nipple discharge.Methods: Between April 2008 and September 2015,a total of 918 patients were diagnosed with nipple discharge and performed by ductoscopy at The Second Affiliated Hospital of Soochow University.It’s clinical manifestations and pathological features are reviewed. All the data was analyzed by IBM SPSS Statistics 20.Results:Among the 918 patients,there were 877 patients performed by fiberoptic ductoscopy successfully.There were 209 patients with mammary duct ectasia,108 with galactophoritis,492 with papillary epithelioma or papillomatosis,11 with breast cancer,and 50 with galactorrhea.Age of onset of intra-duct occupying lesions more then 50 years is statistically significant(?2=42.940,P<0.05).Patients with unilateral nipple discharge are tend to be intra-duct occupying lesions(?2=28.677,P<0.05).Patients with single duct nipple discharge are tend to be intra-duct occupying lesions(?2=36.713,P<0.05).Patients with bloody nipple discharge are tend to be intra-duct occupying lesions(?2=209.824,P<0.05).Patients with or without history of childbearing(?2=0.186,P=0.666) or breastfeeding(?2=1.756,P=0.185) has no statistically significant tend to be intra-duct occupying lesions.Course of disease is no significant difference(?2=3.039,P=0.081).There were 192 patients with intra-duct occupyed lesions were surgically resected,the detection rate of breast cancer with fiberoptic ductoscopy was 72.7%.Conclusion:1.Ductoscopy is the first choice for the diagnosis of nipple discharge.2.Patients older than 50 with unilateral single-duct bloody nipple discharge have high risk of intra-duct occupying lesions.