Analysis Between The Syndromes Of Traditional Chinese And Metabolic Characteristics With Type 2 Diabetes Mellitus In Uygur And Han

Objective: To provide the basis for the different groups in Xinjiang prevention of type 2 diabetes by exploring the distribution of TCM syndromes and metabolic characteristics in Xinjiang Uygur and Han people with type 2 diabetes. Methods: From December 2013 to August 2015, we collected 580 cases of type 2 diabetes patients who are in Xinjiang Uygur Autonomous Region Chinese Medicine Hospital of Endocrinology ward for treatment including Uygur and Han. All cases were classified as type TCM, detected of BMI, waist circumference, fasting plasma glucose(FPG), 2h postprandial blood glucose(2h PG), glycated hemoglobin(Hb A1c), oral glucose tolerance test(OGTT), insulin and C-peptide release test, total cholesterol(TC), triglycerides( TG), high density lipoprotein cholesterol(HDL-C), low density lipoprotein cholesterol(LDL-C) and uric acid(UA), blood urea nitrogen(BUN), creatinine(Cr). Compare of TCM syndrome distribution and metabolic characteristics between Uygur and Han patients with type 2 diabetes, analyse of the relationship between the syndrome and metabolic indicators. Results:(1)TCM syndrome type 2 diabetes from long to short duration were Yin and Yang deficiency, Qi and Yin deficiency, blood stasis context syndrome, spleen phlegm and blood stasis, Yin heat syndrome.(2)Comparing Uygur and Han patients with type 2 diabetes BMI, 2h PG, Hb A1 c, HOMA-IR, HOMA-β, LDL-C, UA, the difference was statistically significant(P<0.05).(3)In different TCM syndromes, Han and Uygur ethnic BMI, Han waist circumference showed the size of Spleen phlegm and blood stasis than other syndromes, the difference was statistically significant(P<0.05). Uygur waist Phlegm spleen showed the highest card, compared with Yin Heat Syndrome、Yin and Yang deficiency、blood stasis context syndrome, the difference was statistically significant(P<0.05). Uygur 2h PG spleen phlegm and blood stasis compared with Qi and Yin Deficiency, Yin and Yang deficiency, blood stasis context syndrome, Hb A1 c spleen phlegm and blood stasis compared with Yin Heat Syndrome, Qi and Yin deficiency, the difference was statistically significant(P<0.05). Comparison of various syndromes, Han and Uygur ethnic HOMA-IR, HOMA-β, the difference was not statistically significant(P>0.05). The highest level of TC, LDL-C is Spleen phlegm and blood stasis in Uygur and Han ethnic groups. TG levels in Han, differences between blood stasis context syndrome and Yin Heat Syndrome, Qi and Yin deficiency, there are statistical significance(P<0.05). The highest level of UA, BUN, Cr is Yin and Yang deficiency in Han and Uygur ethnic groups. UA levels in Uygur groups, Yin and Yang deficiency compared with other syndromes, the difference was statistically significant(P<0.05). Conclusion: In these patients with type 2 diabetes, Qi and Yin deficiency is accounted for the largest proportion in all syndromes. In the Uygur and Han patients with type 2 diabetes, glucose and lipid metabolism, renal function have their own characteristics. Spleen phlegm and blood stasis glycolipid metabolism disorder is the most severe, we need to focus on it. Late lesions of type 2 diabetes is generally Yin and Yang deficiency, during this period we need for timely detection of renal function, it is important to improve the life quality of patients.