The Correlation Between Clinical Prognosis And Uric Acid Level Of Acute Cerebral Infarction

Objective:Aim to explore the association between 3-month clinical outcome and serum uric acid level of acute cerebral infarction.Methods:Selected 335 patients who were diagnosed as acute cerebral infarction from the department of neurology in the 1st Hospital of Jilin University from October 2014 to November 2015 as objects. Clinical data was recorded, and laboratory information which examined in(1.93±1.65)days, including uric acid and other risks of cerebral infarction. Baseline neurological score, clinical outcome(m RS), infarction size are also recorded. Then based on 3-month m RS, serum uric acid level and infarct size divided the patients into different groups. Analyze the data using SPSS 21.0.Outcomes:(1)This study included 335 patients with acute cerebral infarction, female,110cases(33.8%),male,225cases(67.2%),average hospitalization days(10.93±3.42),average age(58.27±11.37), average serum uric acid level(336.2±85.91)μmol/L.(2) UA levels and infarct size had no relevance(r=-0.142,P=0.009).(3)Based on 3-month m RS divided patients into two groups:good outcome(m RS≤2),240cases(71.6%)and poor outcome(m RS>2or death)95cases(28.4%).Elevated serum uric acid was associated with clinical outcome(P<0.05).When adjusted other factors, Elevated uric acid level was still associated with good clinical outcome(P<0.05).(4) Based on UA level divided patients into four groups:3-month m RS was associated with uric acid level(P<0.05),NHISS on admission and discharge had no association with uric acid level(P>0.05).Conclusions:(1)Elevated serum uric acid level was associated with good clinical outcome.(2)Uric acid levels had no association with the severity of acute cerebral infarction.(3)Uric acid levels and infarct size had no relevance.