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Evaluate The Efficacy Of Mai-Wei-Wu-Shen Decoction Stable COPD Lung Andkidney Qi-Yin Deficiency

Posted on:2016-11-28Degree:MasterType:Thesis
Country:ChinaCandidate:H HuangFull Text:PDF
GTID:2284330482458836Subject:Traditional Chinese Medicine
Abstract/Summary:PDF Full Text Request
Objective:Chronic obstructive pulmonary disease before clinical symptoms of stable lung and kidney Qi-Yin deficiency patients,lung function,six-minute walk distance,CATdyspnea grading indicators,evaluation decoction MaiWeiWuShen with conventienal western medicine treatment of chronic obstructive pulmonary disease stabilization period efficacy,and by observing the changes in immune parameters before and after theatment to investigate the mechanisms involved in MaiWei WuShen decoction treatment of COPD.Methods:A randomized,controlled clinical trial methods.In the population of patients with stable COPD lung and kidney QI-Yin deficiency.Select the 60 patients met the inclusion criteria were randomly WM test group used in Thiamethoxam Joe bromide inhalant 18 ug plan based on the specification MaiWei WuShen dely divided into experimental group and control group,the control group received standard treatment progracoction treatment of 3months.Before. clinica lsymptoms were observed total score(cough,sputum,wheezing), Six-minute walk distance,dyspnea grading,lung function and other indicators.Results:From the following three aspects.With conventional western medicine the therapy on lung and kidney Qi-Yin deficiency of lung disease in patients with stable chronic obstructive results are as follows. A clinical efficacyThere after treatment,both groups decrease the points(p<0.05),the experimental group than in the control decreased significantly different(p<0.05).1.1 Clinical symptom score symptom score before treatment was no significant difference (p>0.05)1.21ung function before treatment FVC,FEV1,FEV1%,FEV1/FVC,and other indications no significant difference;After treatment,the test group the indicators were increased,the control group FEV1,FEV1/FVC,beforeFEV1,comparedwith treatment increased.FVC,FEV1% increased obvious;A significant difference the test group than the control group FEV1/FVC,fevl increased,FVC,FEV1% increase was no significant difference (p>0.05)1.3 Six-minute walk distance(6MWD);After treatment,both groups 6MWD were in creased (p<0.01),the experimental group than in the control group increased significantly different(P<0.05).2.The treatment group before and after treatment of traditional Chinese medical syndrome of comparison.All have significant difference(P<0.05);Control group in cough,sputum, wheezing compared with before treatment,also improved(p<0.05).Compared two groups of curative effect of traditional Chinese medicine,treatment group total effective rate was 93.33%,control group total effective rate was 83.33%,compared two groups of curative effect have significant difference (p<0.05),shows that the curative effect of treatment group is better than the control group.3.Safety indexResults there were no significant differences in examination of blood,urine,feces,liver and kidney function and electro cardiogram before and after treatment.No serious adverse events occurred during the test.Conclusions:After the treatment period,both groups of patients in terms of lung function,clinical symptoms and signs,dyspnea and exercise capacity grading were improved,including the experimental group improved significantly compared with the control group that combines MaiWei WuShen decoction therapy with Thiamethoxam Joe bromide inhalant 18 ug for the treatment of effective method of stable COPD lung ang kidney Qi-Yin deficiency.
Keywords/Search Tags:obstructive, pulmonary disease, stable, lung and kidney Qi-Yin deficiency
PDF Full Text Request
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