Objective:To investigate the curative effect and treatment-related adverse reactions of ultrasound mediated targeted drug delivery technology on joint pain.Methods:The patients with joint pain were randomly divided into the experimental group (137 cases) and the control group (138 cases). The ultrasound mediated targeted drug delivery technology was used in the experimental group and the computer intermediate frequency was applied to the control group. The patients of two groups were treated for 20 minutes each time,1 time a day,10 days was one period of treatment. All patients need to accomplish 3 period of treatment. In the study, the pain visual analogue scale (VAS)joint function, ESR,CRP,liver function,renal function and blood routine test were observed before and after the treatment.Results:The effective rate of VAS of experimental group was 92.70%, and the rate of the control group was 81.88%,which had showed significant difference between the two groups.Compared with the control group,the joint function of experimental group was improved markedly. After treatment, the ESR and CRP are significantly lower, but the degree of decline of the ESR and CRP in the two group has no statistical significance.There was no adverse reaction in both groups.Conclusion:Considering good therapeutic effect and no adverse reaction on joint pain, ultrasound mediated drug targeting delivery technology is worthy of promotion. |