Analysis Of Gestational Thyroid Function Of FT3，FT4，TSH

Objective:The subject of the selected singleton pregnancy thyroid function tests, thyroid function through analysis of the data on the prevalence of thyroid function in pregnant women in the region were initially understand, analyze pregnancy early, middle, late prevalence of thyroid function and to explore its possible reasons. While population prevalence of pregnant women and physical examination were analyzed to provide reference and basis for a variety of clinical thyroid disease during pregnancy, provide reference data for specific laboratory diagnostic criteria for groping women in the region of pregnancy, during pregnancy, thyroid and reproductive knowledge the promotion is significant.Methods:1.Collected in May 2013-2014 May our hospital outpatient prenatal and obstetric hospital delivery of a total of 805 cases of singleton pregnancy. Collected in the same period of non-pregnant women in our hospital examination of 103 cases, selected age differences were excluded, no history of thyroid disease were readme, no angiographic recent class not taking estrogen-containing drugs and recent( 6 months), within mirror pancreatic catheter angiography(ERCP) such as the use of iodine contrast agent.2.On selected subjects fasting venous blood 3ml BD companies in the United States to promote the production of yellow inner tube coagulation, after standing at room temperature for 20 min, 3000r/min centrifugation eight minutes to separate the serum according to standard SOP documents in Germany Roche Cobas6000 ECL make the analyzer operation, serum samples FT3, FT4 and TSH, and the data is entered into the computer to save.3.By 2011 the American Thyroid Association(ATA) is recommended to pregnantwomen divided into early, middle and late three, were the first trimester(1-12 weeks),the second trimester(13-27 weeks), the third trimester(28 weeks-delivery), pregnancy cycle by the hospital obstetrician by the last menstrual period and the type-B ultrasonic inspection.Results:1.The same period in 805 cases of pregnant women and physical examination of 103 cases of thyroid function of pregnant women, the results were statistically analyzed,pregnant women set of thyroid function in 288 patients(35.78%), abnormal physical women group of thyroid function was abnormal in 16(16.54%), the difference was statistically significant(P<0.05).2.Pregnant women groups had subclinical hypothyroidism in 173 patients(21.49%),medical women’s groups had subclinical hypothyroidism in 12 cases(11.65%),comparison between the two has a different meaning(P < 0.05), suggesting pregnant women suffering from subclinical hypothyroidism higher than normal women.3.Pregnant women suffering from hypothyroidism set of 40 cases(4.97%), physical examination of women in the group without with the shaped gland hypothyroidism,the difference was statistically significant(P<0.05).4.Pregnant women with low thyroid hormone levels set of 54cases(6.71%),physical examination without suffering from low thyroid hormone levels in women group, comparison between the two has a different meaning(P < 0.05).5.2011 the American thyroid association(ATA) recommends pregnant women can be divided into early pregnancy(1-12 weeks), mid pregnancy(13-27 weeks), late pregnancy(28-delivery).The early, middle and late pregnancy is statistical analysis of thyroid disease, the difference was statistically significant(P<0.05).6.Of pregnancy with subclinical hypothyroidism were analyzed, the pregnancy early and mid pregnancy differences had no statistical significance(P>0.0167);Mid and late pregnancy, respectively, and the early stages of pregnancy pregnant comparison, the difference was statistically significant(P<0.0167).7.Pregnancy early, middle and late three suffer from hypothyroidism were analyzed,the results indicate pregnancy early, middle and late was no significant difference(P>0.0167).8.On the pregnancy with low thyroid hormone levels were analyzed, there was no statistically significant difference at early and mid pregnancy(P>0.0167);Mid and late pregnancy, respectively, and the early stages of pregnancy pregnant comparison, the difference was statistically significant(P<0.0167).9.In pregnant women in the group with 173 cases of subclinical hypothyroidism(21.49%),40cases(4.97%),with hypothyroidism for comparative analysis, comparison between the two has a different meaning(P<0.05).Conclusions:1.Women during pregnancy than non-pregnant women physical examination, may be predisposed to thyroid disease.2.In pregnant women in the group with a subclinical hypothyroidism,hypothyroidism and low thyroid hormone levels is higher than that of non pregnancy check-up.3.In pregnancy early, middle and late periods of thyroid disease in the third phase of situation is there are differences, in the late pregnancy, respectively, compared with early, middle, thyroid disease is not the same, including subclinical hypothyroidism and low thyroid hormone levels of disease.4.In early and mid pregnancy there is no difference between thyroid disease,including in the area of clinical hypothyroidism, hypothyroidism and low thyroid hormone levels, the disease had no difference.5.Pregnant women susceptible to subclinical hypothyroidism and hypothyroidism,which up to a maximum of subclinical hypothyroidism.