| Aim:Summarized and retrospectively analyzed the domestic eosinophilic gastroenteritis(Eosinophilic Gastroenteritis, EG) clinical characteristics of the patients and to improve the knowledge of this disease, and provide early diagnosis and treatment of clues, to reduce the misdiagnosis rate.Methods:Collect 36 cases diagnosed in our country from 2009 January to 2014 January published as a case report of EG patients, classified and analysis of these cases report.Results:1.The general information: 36 cases of EG patients, according to the Klein ’s type,will be divided into 3 groups, group I: II group: mucosal type 18, serosal type 2, group III: mixed type 16(also involving the mucosa and serosa).2.predisposing factors and allergic history: in 36 patients, the incidence of food before clear incentives of the 7 cases, 6 cases had history of allergic reactions, including drug or food allergy, asthma, skin allergies, allergic reaction history of patients from group I and group III, group II patients had no allergy history.3.clinical symptoms: 36 cases of EG patients have different degree of gastrointestinal symptoms, the most common clinical symptoms were abdominal pain(27/36, 75%), mainly located in the upper abdomen, and abdominal distension, diarrhea,nausea and vomiting, weight loss, bowel exhaust reduction.4. peripheral blood, stool routine: the 36 EG patients, 30 cases of peripheral white blood cell count increased(30/36 83.33%), peripheral blood eosinophil count increased in 33 cases(33/36 91.67%), all the patients peripheral blood eosinophil percentage wereincreased in I group, peripheral blood eosinophil granulocyte count and II group had no significant difference(P > 0.05) compared. 10 cases of occult blood positive(27.78%)5.bone marrow puncture, the ascites: bone marrow puncture in 14 cases, showed eosinophilia, and increase in mature stage. 17 cases of peritoneal effusion ascites were positive, exudate, the appearance of yellow turbid in 13 cases, 3 cases of bloody ascites,1 cases of chylous ascites, peritoneal cytology examination showed elevated eosinophil percentages.6.Serological examination: 36 cases of EG patients, the laboratory ESR in 5 cases(13.89%), 2 patients with elevated serum Ig E(5.56%), 2 cases of tumor marker CA125increased(5.56%), C-reactive protein(elevated), autoantibodies tests showed no abnormality.7.endoscopy and biopsy of 36 patients with EG, 27 cases underwent gastroscopy,colonoscopy in 11 cases, endoscopic mainly for mucosal hyperemia and edema, erosion,eosinophil infiltration were seen in pathological examination.8.Imaging examination:36 patients with EG of line of abdominal ultrasound examination in 17 patients with ascites,bowel wall thickening in 1 cases.9.treatment: 36 cases of EG patients were treated with hormone, 3-7 days, gastrointestinal symptoms were relieved, symptoms disappeared within 2 week completely,and the white blood cells, eosinophils recovered normal. Compared before and after treatment of white blood cells, eosinophil count the difference had statistical significance.Conclusion:The etiology and pathoqenesis of EG is still not entirely dear,speculation is associated with allergic or immune response.Clinical manifestations of EG is diversity,the lack of specific, for abdominal pain, abdominal distension and diarrhea, nausea and vomiting associated with peripheral blood eosinophilia patients should be alert to this disease. Its main endoscopic pathology showed mucosal hyperemia, edema,erosion.Steroids remain the mainstay of therapy for eosinophilic gastroenteritis,and the effect is well.Relapse can occur after steroids therapy. |
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