The Research Of Acute Bronchitis Dialectics And Herbs Based On Famous TCM Doctor’s Experience

Objective: Establish a "modern old TCM doctor’s diagnosis Acute Bronchi tis literature database. Analyzing Modern old TCM doctor’s treating experiences and drug laws on Acute Bronchitis. In order to provide scientific basis for Ac ute Bronchitis.Methods:Using the literature about the modern old TCM doctor’s experien ce of diagnosis and treatment of Acute Bronchitis, which from "Modern lung ol d TCM doctor Database" and "pulmonary medicine journals Database", establish ing a "modern old TCM doctor’s diagnosis Acute Bronchitis literature database".Using descriptive analysis, cluster analysis,and factor analysis.Summarize the dis tribution of Acute Bronchitis,syndrome element distribution and composition,co mmon syndrome,prescription compatibility law.Results: Filtered according to the inclusion criteria and exclusion criteria, the data of 1032, 620 including etiology, and 687 pathogenesis, 184 syndrome,956 kinds of Chinese medicine, 405 prescriptions. 1 Pathogenesis distribution: 18 kinds of Acute Bronchitis etiology, which High frequency include:six evils(34.5%),wind(27.7%),Fire evil(24.4%),external(20.3%),sputum(18.7%), cold(17.9%);87 kinds of pathogenesis, which frequency > 5 % as follows: Fei shi xuan su(17.3%), Accumulation of phlegm and heat in the lung(9.9%),wind-cold invading lung(9.5%), Sputum and dampness pathogen obstructing the lung(8.3%), wind-heat invading lung(8.1%),Qi deficiency of the spleen(5.1%),wind-dryness invading lung(6.0%) 2 The Combination and distribution of syndrome element : syndrome element o f etiology heat(52.7%), wind(45.1%),sputum(32.1%), cold(30.9%), common disea se location is lung, spleen, liver, kidney.The combination rule was dominated b y the combination of three syndrome elements and two syndrome elements. For the combination of syndrome elements of disease nature and disease location,the common single syndrome elements of disease nature were Qi deficiency, he at, yin deficiency,dryness pathogen.The disease locations were mainly the lung, the spleen,the kidney and liver.The combination of two syndrome elements of disease nature were wind pathogen combined with cold pathogen, the sputum p athogen combined with heat pathogen, wind pathogen combined with heat patho gen, the sputum pathogencombined with damp pathogen,The disease locations w ere mainly the lung. 3 Common syndrome:A total of 43 syndromes,frequency ≥ 5% include:wind-col d attacking lung syndrome(27.7%),phlegm-heat obstructing lung syndrome(20.7%), wind-heat affecting lung syndrome(19%), phlegm obstructing lung syndrom e(12.5%), deficiency of lung-QI syndrome(7.6%), lung heat syndrome(7.1%), def iciency of lung-Yin syndrome(6.0%), dryness invading the lung syndrome(3.3%). 4 Clinical characteristics of syndromes 4.1 wind-cold attacking lung syndrome:①main symptom:Cough, fever, aversion to cold, fever, white tongue coating, pulse floating;②Secondary symptoms:Hea dache, sore throat, runny nose, stuffy nose, chills, thin tongue fur, pulse tight. 4.2 wind-heat affecting lung syndrome:①main symptom:Cough, sputum, fever, hoarseness, floating pulse;②Secondary symptoms:Sticky sputum, dry throat, sor e throat, headache, thin yellow tongue coating, pulse number or white. 4.3 dryness invading the lung syndrome:①main symptom:Cough, cough, phleg m, cough, dry lips;②Secondary symptoms:Dry mouth, thirst, dry throat, itchy t hroat, sputum, hemoptysis, chest tightness, difficult to spit red complexion, con stipation, urine, red tongue, Huang Chi, white or yellow fur, pulse number or dry. 4.4 phlegm obstructing lung syndrome:①main symptom:Cough, phlegm, phlegm, sputum white sticky, slippery pulse;②Secondary symptoms:Vomiting, diarrhea, red tongue, thick and greasy tongue coating or thin white, pulse moisten. 4.5 phlegm-heat obstructing lung syndrome:①main symptom:Cough, yellow sput um, red tongue, yellow tongue fur, pulse number;②Secondary symptoms:Fever, dyspnea, wheezing, wheezing sound in the throat, dry mouth, slippery pulse. 4.6 deficiency of lung-QI syndrome:①main symptom:Cough;②Secondary sympto ms:Fever, sputum, red tongue, thready pulse or number. 5 Common Prescription :frequency ≥ 3% include: Ma Xing Shi Gan Tang(11.4%), Zhi Sou San(10.1%), Er Chen decoction(5.9%),Apricot Kernel and PerillaPowder(5.4%), Sang Ju Yin(5.4%), Xiao Qinglong Tang(4.4%), San Ao Tang(4.4%). 6 Analysis of drugs for acute bronchitis:frequency ≥ 15% include:almond(65.9%), Licorice(59.7%), Fritillaria cirrhosa(35.8%), Bellflower(34.6%), Pinellia(31.8%), Aster(25.5%), Ephdra(24.3%), Citrus(23.7%), Angelica(23.7%), Skullcap(23.5%), Poria(23.4%), Loquat(22.7%), Melon(21.3%), Suzi(19.9%), Fritillaria(18%), Morus alba(16.9%), Mulberry(16.0%), Radix(15.5%), Ophiopogon root(15.1%). 7 The Common syndrome pharmaceutical analysis 7.1 Wind-cold attacking lung syndrome:Three bend soup, Xinsu powder,Small Qinglong Decoction, Maxingshigan Decoction, Zhisou powder;Ephedra, licorice, ginger, cinnamon, Platycodon grandiflorum, orange, white, aster, Stemona, Flos farfarae, Schizonepeta, perilla leaf, Radix Peucedani, almond, pinellia, Perilla. 7.2 Wind-heat affecting lung syndrome: Sang Juyin,Maxingshigan Decoction; C hrysanthemum, honeysuckle, forsythia, arctium fruit, mint, mulberry leaf, root, a ster, Morus alba, Rhizoma Anemarrhenae, baikal skullcap root, perilla seed, Fru ctus Trichosanthis,almond, loquat leaf, licorice, Campanulaceae, Fritillaria, Radix Peucedani. 7.3 Dryness invading the lung syndrome: Sang Xing Decoction, Three bend soup; Nansha ginseng, Radix Glehniae, ophiopogon root, trichosanthes root, loquat leaf, Fritillaria, reed root, aster, Radix Scutellariae, Pang Dahai, agrimony, sunburn licorice, mulberry bark, lily, Cortex Moutan, mulberry leaf, chrysanthemum, cassia twig, licorice, ephedra, almond, Radix. 7.4 Pulmonary stagnation of phlegm syndrome: Two Chen Tang, Three bend so up, Zhisou powder, Maxingshigan Decoction, Sanzhiyangqinsoup;Poria cocos, pi nellia, dried orange peel, orange, melon seed, coix seed, Stemona, aster, white,perilla seed, semen persicae, Rhizoma Phragmitis, Fritillaria, snakegourd fruit, r adish seed, mulberry bark, licorice, ephedra, almond. 7.5 Phlegm-heat obstructing lung syndrome:Maxingshigan Decoction, Zhisou po wder, Xiebai powder; Ephedra,almond, licorice, honeysuckle, reed root, Platycod on grandiflorum, Radix Peucedani, Stemona, aster, pummelopeel, Fritillaria, peri lla seed, Morus alba, loquat leaf, peach kernel, pinellia, Poria, Fructus aurantii. 7.6 Deficiency of lung-YI syndrome: Qingfei powder; Almonds, Fritillaria,Bellf lower, Aster, Scrophulariaceae, Radix, Phragmites, Licorice, Suzi,Baiqian, Coltsf oot flower, Stemona, yam.8 Canonical correlation analysis between the symptoms and Medicine 8.1 The first pair of canonical variables:V1(Fever, headache, dry mouth, floating pulse,stuffynose,sorethroat,putumsmears,Red complexion);W1(bellflower, Fritillariae thunbergii, Mulberry leaves, white front, pericarpium trichosanthis, Nepeta, mint). 8.2 The second pair of canonical variables:V2(Red tongue, slippery pulse, fever, dry mouth, throat itching, cough, sputum less); W2(Aster, perilla seed, mulberry leaf, Radix Ophiopogonis, Bai Qian, almond, Radix Stemonae). 8.3 The third pair of canonical variables:V3(White moss, pulse number, veinlets, wheezing, cough, dry throat, Taut Pulse); W3(Adenophora, Rhizoma Anemarrhenae, ginger, licorice, Radix Scrophulariae, asparagus, sweet basil). 8.4 The fourth pair of canonical variables:V4(Red tongue, yellow moss, pulse, fever, anorexia, wheezing sound in the throat, dry throat, yellow urine, yellow sputum, dyspnea); W4(Bulbus Fritillariae Cirrhosae, Pericarpium Citri Reticulatae, radix, Radix Ophiopogonis, gypsum, Rhizoma Pinelliae, reed rhizome, Herba Houttuyniae, semen Lepidii, Xuan Can). 8.5 The fifth pair of canonical variables:V5(Slippery pulse, white sputum, sticky sputum, greasy fur); W5(Tuckahoe, coix seed). 8.6 The sixth pair of canonical variables:V6(Thin coating, floating pulse, itchy throat, sputum, fever, slow pulse, pale tongue); W6(Ephedra, perilla seed, cassia twig, ginger, wind). 8.7 The seventh pair of canonical variables:V7(Little sputum, thirst, yellow urination, sweating); W7(Schisandra chinensis, Radix trichosanthis, Radix Ophiopogonis). 8.8 The eighth pair of canonical variables:V8(Chest tightness, dry mouth, dry cough, phlegm, phlegm); W8(snakegourd fruit, Citrus grandis, coltsfoot flower, almond, radix rehmanniae, clam shell). 8.9 The ninth pair of canonical variables:V9(White fur, anorexia, Tan Bai); W9(Licorice root, pinellia tuber, Atractylodes, Radix Peucedani).Conclusion: 1 The main cause is the external, the pathogenic wind for the pilot, often with cold, heat evil, evil dryness, dampness;The main pathogenesis of wind cold attacking the lung, lung loses Xuan Su. 2 The syndrome element combination of Acute Bronchitis is mainly the combin ation of three elements, and the combination with the highest frequency is win d pathogen, cold pathogen and the lung.3 The main syndrome elements of Acute Bronchitis, the element of disease location is mainly the lung. The elements of disease nature are mainly heat,wind, cold,and sputum. 4 The common syndromes for Acute Bronchitis are wind-cold obstructing the l ung syndrome, wind-heat attacking the lung syndrome,dryness injuring the lungs yndrome,dampness obstructing the lung syndrome,phlegm-heat obstructing lung s yndrome, lung-yin deficiency syndrome,. 5 The old doctor of traditional Chinese medicine in the treatment of relieving cough and asthma drugs for acute bronchitis,clip permits or certificates when the solution of drug addition and subtraction with the jiebiao medicine, antipyretic, tonic and other various medicine.