The Clinical Observation On Early Type 2 Of Incipient Diabetic Neuropathy Is Treated By Liuweidihuang Tang Flavored Combined With Enalaprilat

Objective This topic through the observation of treatment with the method for Liuweidihuang tang flavored combined with Enalaprilat on changes in Patients with early type 2 of incipient diabetic neuropathy(deficiency of both qi and Yin),observe the effect clinical curative or the clinical indicators changes.Methods 40 cases of patients diagnosed with early type 2 diabetic neuropathy were randomly divided into two groups,the treatment group of 20 patients and a control group of 20 patients.and both groups were given glucose, blood pressure,lipid lowering treatment and other infrastructure.The control group received enalaprilat 10mg/day, orally; In addition,treatment group were equipped with treatment based on traditional Chinese medicine, party election Liuweidihuang tang flavored by the hospital pharmacy unified generation fried, according to a daily dose of the liquid concentrate distributed into two bags, each bag of 150 ml, every bag, breakfast, half an hour after dinner, warm clothes.4 weeks for a course, for taking two courses.We should observe all of the patients, treatment efficiency, symptoms cores before and after,clinical symptoms and signs, blood fat,the excretion rate of urinary albumin、C-reactive protein and safety indicators.Results ①the treatment group total efficiency(90%)and the control group, the total efficiency(50%)are more differences(P<0.05);②the treatment group had in improving the signs and symptoms in patients with individual aspects of traditional Chinese medicine and control group(P<0.05);Especially the lazy languid, thirst with liking for fluids,soreness and weakness of waist and knees, dizziness tinnitus and spontaneous sweating were improved obviously(P<0.05);③Before treatment,the syndrome was no differ-ence in total score(P>0.05);The two groups after treatment of syndrome was to compare the total integral have difference(P<0.05), and the total score after treatment syndromes between the two groups was significant difference(P<0.05): ④ two the serum C-reactive protein comparison: The two groups before treatment the serum CRP level was no difference(P>0.05),Two groups after treatment serum CRP levels are difference compared with before treatment(P<0.05); And there were differences between the serum CRP comparison between the two groups after treatment(P<0.05); ⑤ two urinary albumin excretion rate(UAER) comparison: no difference between the two groups before treatment UAER(P>0.05), no statistically signific-ant, comparable; two groups with UAER was compare have the significant difference after treatment(P<0.05);And after the treatment of UAER comparison between the two groups had significant difference(P<0.05);⑥two groups before treatment,FBG, 2h PG,HbA1 C were no differences in comparison(P>0.05);there was differences in FBG(P<0.05)compared with before their treatment,but there was no difference(P>0.05)between groups in 2hPG and HbA1 C compared with before their treatment(P>0.05)⑦The serum TC,TG,HDL-C,LDL-C with in the group,between the two groups had no difference(P>0.05);And after the treatment comparison between the two groups had significant difference(P<0.05)⑧the whole treatment process, each containing two groups of patients with slight cough symptoms, the treatment group have 1 case of mild symptoms of dizziness, but all can tolerate, continue to complete the entire clinical observat-ion,no other obvious adverse reaction, the safety index is normal, no case fall off.Conclusion Compared with enalaprilat alone, using Liuweidi-huang tang flavored therapy of early type 2 diabetic neuropathy(deficiency of both qi and yin) patients:①can improve the total effective rate of treatment;②patients are better able to reduce syndromes total points and improve the clinical symptoms of tradi-tional Chinese medicine to improve the quality of life of patients;③can better improve the patients serum CRP level, reduce the blood vessels in patients with inflammatory response;④can be more great-ly reduce the UAER of patients, reduce the excretion of urine albumin, in order to delay the progress of kidney damage; And in the process of the treatment did not appear obvious adverse reac-tions.Considerable, security, good curative effect, worth clini-cal promotion.