Clinical Study On The Improvement Of Chronichepatitis Related Disorders Of Glucose Metabolism Jianpihuashi Huoshijiedu Method

The purpose:The clinical curative effect of improve glucose metabolism disorders in HBV related chronic liver disease complicated with jianpihuashi and huoxuejiedu method,confirm the possible mechanism and action target point improve glucose metabolism disorders in HBV related chronic liver disease complicated with jianpihuashi and huoxuejiedu method.Methods:This topic in 60 patients with HBV related chronic liver disease in sugar metabolism disorder patients as the research object,by jianpihuashi and huoxuejiedu therapy for threemonths,the clinical curative effect and mechanism of antion of summing up jianpihuashi and huoxuejiedu method in the treatment of HBV related chronic liver disease in sugar metabolism disorder.Results:Jianpihuashi and huoxuejiedu method in the treatment of HBV related c hronic liver disease in sugar metabolism disorders,100% of the total clinical effic acy; To improve the total efficiency of TCM syndromes of 100%;GLU,2h GLU,C peptide(P<0.01),HbA1c(P<0.05),glucose metabolism index improved obviousl y;ALT,AST,GGT decreased significantly(P<0.01);TP,A increased significantl y(P<0.05),liver function improved obviously;2hINS,INS decreased significantly(P<0.01),ISI decreased significantly,βcell function index increased(P<0.05),the seru m levels of anti insulin antibody,islet cell antibody significantly reduced(P<0.01),i slet function and insulin release significantly improved;Adiponectin was significantly increased(P<0.01),leptin, tumor,necrosisfactor decreased significantly(P<0.05),ins ulin growth factor significantly increased(P<0.05),the related cytokines significantly improved;insulin receptor substrate-1 decreased significantly(P<0.01);endotoxin decreased significantly(P<0.01).Conclusion: Jianpihuashi and huoxuejiedu method can effectively improve the HBV related chronic liver disease in glucose metabolism,improve the sensitivity of insulin,repair of the liver’s injury,restore the function of pancreas,improve the clinical symptoms and signs,improve the quality of life.