| The purpose: To invigorating spleen for eliminating dampness and promoting bloodcirculation and detoxication method group parties, oral treatment for3months to observethe improvement of the clinical efficacy of HBV-related chronic liver disease disorder ofglucose metabolism, and to explore its mechanism.Methods: The subjects invigorating spleen for eliminating dampness and promotingblood circulation and detoxication method prescriptions to treat40patients withHBV-related chronic liver disease of sugar metabolism disorder patients, through theinvestigation of the clinical data, analysis of the efficacy of medical treatment improveglucose metabolism disorders, summed spleen of wet, blood detoxification treatment ofHBV-related chronic liver disease disorder of glucose metabolism, clinical efficacy.Results: Improve the disorder in patients with HBV related chronic liver disease ofsugar metabolism invigorating spleen for eliminating dampness and promoting bloodcirculation and detoxication method, the total clinical cure rate100%,2cases were cured,24cases markedly effective, effective14cases, invalid0cases; TCM syndrome curativeeffect the total efficiency of100%, of which18cases were markedly effective, effective20 cases, invalid0cases; ALT, AST, GGT, TBIL, GLU,2hGLU, INS,2hINS weresignificantly reduced compared with before treatment, there were significant differences (P<0.01); TP, ALB compared with before treatment increased, there was a significantdifference (P <0.01); insulin sensitive index, beta function index increased significantly,insulin resistance index decreased significantly, there is significant differences (P <0.01);serum endotoxin levels were significantly lower after treatment, there was significantdifference compared with that before treatment (P <0.01); abdominal B ultrasoundseverity decreased after treatment, there was significant difference compared with thatbefore treatment (P <0.01); patients symptoms scores lower, have very significantdifference compared with before treatment (P <0.01); the patients after treatment thanbefore treatment in chronic elevated points table, disease symptoms, life affected lowerthan before treatment, emotional stability, and before treatment was a very significantdifference (P <0.01); the patients after treatment than before treatment to reduce the degreeof fatigue, there was a significant difference compared with that before treatment (P<0.01).Conclusion: invigorating spleen for eliminating dampness and promoting bloodcirculation and detoxication method can effectively improve glucose metabolism disordersHBV-related chronic liver disease, lower blood sugar, improve insulin sensitivity, repairliver function, improving the clinical signs and symptoms, improve quality of life. |