Comparison Of Laparoscopic Retroperitioneal Radical Nephrectomy And Open Radical Nephrectomy In T2Renal Cell Carcinoma

Objective:To evaluate the clinical application value of retroperitoneal laparoscopicradical nephrectomy in T2renal cell carcinoma(RCC).Methods:56patients with T2renal cell carcinoma were retrospectively analyzed fromFebruar,2007to Februar，2010.24patients (18Males and6Females) were receivedretroperitoneoscopic radical nephrectomy(RPN);32patients (23Males and9Females)were received open radical nephrectomy (ORN).The operation time,blood loss volumeduring operation,bowel function recovery,hospital stay and postoperativecomplications were compared in two groups.Results:The operative time in the ORN group (166.30±28.20min) was significantlyshorter than that in the RPN group (188.20±27.40min),P<0.05.The estimated bloodloss volume in the RPN group (285.10±220.20ml) was also significantly less than inthe ORN group(446.20±273.40ml), P<0.05. Patients in RPN group experiencedsignificantly shorter bowel function recovery and ambulation time than those in theORN group after operation. All Patients were followed up for36~60months， Thepostoperative metastasis rate was12.5%in RPN group， and was16.7%in OPNgroup. No severe perioperative complications occurred. Kaplan-Meier survival curvesshowed that the followed up for survival rates of the two groups had no statisticallysignificant difference, P＞0.05.Conclusions:The data indicates that the RPN for T2renal cancer treatment is safe andeffective. Compared with OPN， RPN has less blood loss， faster postoperative intestine recovery， earlier ambulation， shorter hospital stay.