| Backgrounds and Objectives: Anterior cruciate ligament(ACL) does not only work asa dynamic balance structure in biomechanics, it also provides some function forproprioception. The proprioception of knee is an important mechanism to maintaindynamics stability. The proprioception of knee comes from the capsule、meniscus、periarticular muscle、ligament and skinetc. It proves that cerebral motor cortex will firstget the proprioception of bilateral limbs. Then it will adjust the state of the musclespindle with γ motor neuron Finally the abstraction of the muscle around the joint will becontrolled. The proprioception of knee is highly correlated with its functional reflection.The defection of proprioception after the ACL injure is a critical problem. Someresearch has proved that even if the rebuilding is done to maintain the dynamic balanceafter the wound in knee, it is highly possible that the patients will become earlyosteoarthritis. It implies the importance of the proprioception of knee to maintain thedynamic balance. Conservative curing methods are adopted to cure the ACL injure if thewound is light and cause little trouble in maintaining the balance. Clinical research hasproved that the rehabilitation practice won’t relief the defection in proprioception. Mostresearchers thought it is related to the compensatory of proprioception with other bodypart. However, few researches has been done on the situation that whether there is achange in the function, number or shape of the proprioception in the ligament when ACLhas been broken completely and keeps the original location. Also it proves that whensome damage has been done to the ACL, there will be some loss of the proprioception inthe unwounded other side. Much less research has been done on this topic yet. In thatcase, the research on this topic will play a profound and lasting role in curing the damageon ACL. This paper mainly talks about the shape and function changes in Bilateralligaments’proprioceptors caused by the ACL injure in one side.Methods and results:52New Zealand habits are involved in research.45of them, ofwhose ACL are cut and the remaining part of ACL are kept connected, are modeled asunilateral ACL partly injure.7of them are kept as normal matched group.electrophysiology、Gold chloride staining、HRP retrograde tracing are conducted on somehabit after the operation2months,4months and6months later. It shows that theincubation period and wave crest which SEPs and EMG gets longer and lower as time passed. Two groups shows a statistical difference (P<0.05). There is a drop of the percentof the HRP positive area in spinal ganflion on defect side. Gold-chloride staining showsthat the number of sensors gets smaller in ACL and the abnormal ones gets more. The sizeget smaller. There is also some loss in structure. The other side also shows the trend thatSEPs and EMG gets longer and lower as time passed), but there is no statistical differencewith the matched group (P>0.05). The number, shape of proprioceptors in ACL, HRPretrograde tracing shows no significant difference between the ACL model group andmatched group.(P>0.05).Conclusion: The analysis of molecular biology, shape and electrophysiology method onproprioceptors on ACL defection proves that proprioceptors in the ACL will functionnormally in a short time. However, its functionality gets weaker as time passed. Thereason may be related to the slack and weakening caused by the ACL defection. Theproprioceptors can no longer feel the proper force due to it. The proprioception on theother side also shows a drop trend. This may be related to the way that the CNS receivesthe proprioception from Bilateral limbs. The changes on the signal from the injured sidewill affect the contralateral limb’s muscle spindle function and affect the stability of theother side. |
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