Based On The "Contact Poison Intestinal Damage," The Skullcap Vine Yuyang Decoction Remission Of Ulcerative Colitis Clinical Research

Objective: Based on the "contact poison damage gut" hypothesis, applied instructorexperience side skullcap vine Yuyang Tang Ning Tang bowel enema+UC remission oraltreatment to evaluate efficacy, in order to provide new treatment options for TCMtreatment UC.Methods: First, inspect the "poison damage intestinal envelope" literature hypothesisof UC remission TCM etiology, pathogenesis and recurrence factors were analyzed, basedon the principles of treatment applied mentor, Professor Liu Dongmei experience sideenema combined with oral treatment of UC patients in remission in40cases, wererandomly divided into2groups: Only western medicine treatment group and the controlgroup orally. After three courses comparative clinical efficacy observed two groups ofpatients, Colonoscopy and histopathological changes and medication safety.3-monthfollow-up, the relapse rate was observed comparing the two groups of patients.Results: After three experimental treatment group, the total effective rate:90%in thecontrol group, the total effective rate:70%, the difference was statistically significant (P<0.05)；Syndromes comprehensive test group total effective rate was90%in the controlgroup was80%, the difference was statistically significant (P <0.01); experimental groupof diarrhea, blood and pus, abdominal pain, less satisfied, lassitude and weak weakness andother symptoms of improvement than the control group (P <0.05or P <0.01); The mainsymptom scores after treatment comparison P value0.007, there is statistically significant;contrast performance before and after treatment under the colonoscopy, the test group, thetotal efficiency of90%in the control group80%, p=0.048comparing the two groups,there was statistically significant; Mucosa histopathological examination comparison before and after treatment, the test group was:85%in the control group:75%, p=0.033,statistically significant; while comparative analysis of the two groups before and aftertreatment D-dimer, two groups were statistically significant; Security, no liver functionbefore and after treatment, renal function was statistically significant; followed up threemonths later, the number of test group2cases of recurrence, the recurrence rate of10%inthe control group relapsed six people, the recurrence rate of30%, two sets of results werecompared, the difference was statistically significant (P <0.05).Conclusion: Based on the "contact poison intestinal damage," Professor hypothesis,the clinical application of vine Yuyang Liu Dongmei Qin Tang Ning decoction enema withintestinal UC remission maintenance therapy, the clinical efficacy of accurate and reliablein clinical remission, clinical symptoms improved, the main clinical symptoms, improveunder colonoscopy mucosal healing quality, prevention of recurrence has a distinctadvantage. Consider medicine in the treatment of ulcerative colitis, for improve theimmune capacity, improve intestinal microcirculation, improving the relationship betweenintestinal flora, elimination of intestinal inflammation have a role in other aspects.