Study On Adjusting Heart And Kidney On The Elderly Male With Mild Cognitive Impairment

Objective: By adjusting heart and kidney method for male with mild cognitive impairment to intervene, to observe the representative and the change of the inner link of indicators, further validation of traditional Chinese medicine in the treatment of mild cognitive impairment(MCI) of safety, efficacy, and clarify the material basis for the method of adjusting heart and kidney function, mild cognitive impairment were discussed from the point of view of microcosmic syndrome differentiation from the heart the essence of the renal differentiation.Methods: Give priority to with adjustable bushing kidney method for man to intervene,mild cognitive impairment in observation of 60 cases, by random grouping, the treatment group and control group 30 cases, single blind random control method for clinical trials.Treatment group on the basis of always exists disease medication, be adjustable bushing kidney oral, ginseng, radix rehmanniae, notoginseng, cortex moutan, stone calamus, polygala,choose Chinese medicine decoction, free daily 1 bag san-jiu pharmaceutical manufacturing(shenzhen), spray dried pilose antler 1 g daily inquiry, warm water to 200 ml, 2 times.The control group only drugs to treat diseases always exist, continuous administration, a total of12 weeks.Observe the two groups before treatment, treatment after simple mental state scale(MMSE), Montreal cognitive assessment scale(MOCA) and syndromes curative effect,plasma brain natriuretic peptide factor(plasma BNP), estradiol(E2), the change of the serum testosterone(T), verify the bushing kidney method, the curative effect of treatment of mild cognitive impairment, clarify the bushing material base of the kidney function, mild cognitive impairment were discussed from the point of view of microcosmic syndrome differentiation from the heart the essence of the renal differentiation, reveal the bushing kidney and scientific connotation of prevention and treatment of senile dementia.Results: We through this topic confirmed adjustable bushing renal party has a good effect in improving cognitive impairment in older women.Two groups of total clinical curative effect comparison, the treatment group total effective rate was 58.6%, 7.1% better than that of control group(P < 0.05).Treatment group can improve the weakness of shortness of breath, lumbar debility, tinnitus, dizziness, palpitation, good afraid of yi jing, complexionShaoHua, the symptom such as insomnia and less obviously better than that of control group(P < 0.05).Two groups of neuropsychological scale scores compared before and after treatment, the treatment group was higher than control group(P < 0.05).Plasma BNP, serum E2 and T levels were observed, plasma BNP levels in treatment group after treatment, serum E2 and T levels increase(P < 0.05).Conclusion: Based on the method of adjusting heart and kidney can adjust the plasma BNP, the level of serum E2, T, to achieve a better mousetrap, the role of the kidney essence,thus proves from the angle of microcosmic syndrome differentiation, the bushing kidney in the treatment of mild cognitive impairment is effective, which provides a new way for prevention and treatment of senile dementia.