| Objective:Used functional magnetic resonance imaging (fMRI) to observe the curative and hand needle stimulation instant effect and accumulated effect of electric acupuncture and hand needle stimulation effects on brain function, in order to further explain acupuncture will provide a scientific basis for the central nervous system.Methods:This test according to test the inclusion criteria, exclusion criteria selection 12 healthy adults, male and female ratio of 1:1, and the electric acupuncture and hand needle stimulation experiment was carried out respectively.1 week before the test to give participants’line of electric acupuncture and hand needle stimulation experiments, and record test data, in the process of the experimental subjects were removed 2 people. Official test process for the first three mile, outside points hand needle stimulation, torsional amplitude+180 hand needle group, the frequency is 60 times/min. Line 1 week after electroacupuncture, electric acupuncture group with continuous wave, frequency of 2 hz. The real test process is rigorous, results. Test method of blood oxygen level dependent (blood oxygenation level dependent, BOLD) fMRI technology subjects test data, test using Block pattern design, application NATLAB R2014a SPM12 software package of image processing and statistical analysis, xjview application softwa。Results:Needle, electric acupuncture, and one hand to stimulate the immediate effects of contrast research1. Electric acupuncture (EA) compared with hand needle (MA) stimulation with immediate effect, found that both stimulation activated contralateral primary somatic motor area (M1), bilateral first somatosensory area (S1), cupping and specificity to activate the premotor (PM). In the contralateral S I, hand needle activation intensity is stronger, will activate the area is larger. Electric acupuncture and hand needle is negative to activate the ipsilateral M,2. Electric acupuncture significantly and hand hand needle significantly cupping the immediate effect of contrast, the study found the curative hand significantly activated brain regions on the same side as the needle. Ipsilateral M1, supplementary motor area (SMA), back in frontal, top down last time, on the right side of the temporal lobe is activated. Hand needle acusector show significantly activated brain regions in the contralateral to the, to the edge of the side lobe, superior temporal gyrus, cerebellum posterior lobe, ipsilateral superior temporal gyrus is activated. Second, the accumulation of electric acupuncture and hand needle stimulation effect of comparative study1. The cumulative effect of electroacupuncture contrast found, S1, S2, S3 are significantly activated is given priority to with the contralateral areas of the brain, activation of the contralateral M1, S1, edge, ipsilateral cerebellum, precuneus. Activated brain regions in S1, S2, S3 phase area from small to large order of S2, S3, S1. In the contralateral primary body movement area and the first somatosensory area, S1 to stimulate the strength strongest, followed by S2, S3 is once again.2. Hand needle stimulation found that the cumulative effect of contrast, S1, S2, S3 are significantly activated is given priority to with the contralateral areas of the brain, activation of the contralateral M1, S1, ipsilateral cerebellum. Activated by small area and activate the strength to arrange respectively is:S3 and S2 and S1. Three, different acupuncture method on the comparative study of brain function1. Electric acupuncture needle stimulation and hand contrast research of brain functionCupping is significantly activated areas of the brain most of the distribution is symmetrical. Cupping is activated bilateral M1,S1, cerebellum, contralateral frontal gyrus. edge of leaf (cingulate) significantly activated significantly activated; Cupping negative activates the edges on both sides of the leaf (parahippocampal gyrus), precuneus.Hand needle is significantly activated brain areas on both sides, mostly in the contralateral hemisphere, double side S1, M1, superior temporal gyrus, top lobule, the cerebellum, the insula is significantly activated. In addition, the hand needle is also activate ipsilateral auxiliary motor area in return, edge, inferior frontal gyrus, frontal lobe, cerebellum anterior lobe and a significant activation in lentiform nucleus and thalamus. Hand needle negative activates the negative activate other nuclei.Electric acupuncture and hand needle activates the bilateral M1,S1, the cerebellum. Will activate areas of the brain most of the distribution is symmetrical, activate the hand needle is given priority to with the contralateral areas of the brain; Hand needle will activate a wider, activate the strength of stronger cupping a hand needle.2. Electric acupuncture significantly and hand hand needle cupping of the comparison of the activation of brain function significantly Electric acupuncture hand needle significantly activated brain regions mostly in ipsilateral hemisphere, activate the strength in the ipsilateral superior temporal gyrus, temporal back. Back to be pronounced in the bilateral temporal activation, on the same side of the primary body movement area, the supplementary motor area, frontal last time, inferior frontal gyrus, hat with a significant lobule, the insula activation.Hand needle acusector significantly activated brain regions mostly in the contralateral hemisphere. Activate the strength for the edge on the right side of the leaf. Including hand needle significantly activated back in to the edge of the side lobe, the forehead, the cerebellum posterior lobe; On the left side of the forehead last time there was a significant activation.Conclusions:1. The curative and hand needle stimulation activated brain regions were observed with immediate effect and cumulative effect, and as the change of time, the brain functional areas was also changing.2. The curative and hand needle stimulation to activate the central back before and after the central back, in return, the superior temporal gyrus, frontal lobules, cerebellum, and many other brain regions, but the intensity of the cupping a hand needle activation was stronger, hand needle will activate a wider range of cupping activate areas of the brain were more symmetrical distribution, hand needle activation areas of the brain is given priority to with the contralateral more.3. The curative and hand needle stimulation in brain regions associated with movement, in addition to the outside part of the activation of contralateral primary motor area, secondary can be obviously activated motor areas on both sides, ipsilateral cerebellum see also part of the activation, provided the scientific basis for motor dysfunction disease treatment. |
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