The Research Of The Application Of MUST In Hospitalized Patients With Inflammatory Bowel Disease

Objective:1. To analyze the applicability of using MUST to screen nutritional risk in hospitalized patients with IBD;2. To analyze the distribution of traditional nutrition indicators of having nutritional risk group and no nutrition risk group;3. To analyze the relationship between nutritional risk and clinical outcome;4. To explore the factors influencing the nutritional risk of IBD, in order to provide theoretical and practical basis for further study,prevent and treat the malnutrition of IBD.Methed: An analytic study was carried out,The purposive sampling method was used to select the hospitalized patients with IBD at the Gastroenterology Department of the third hospital affiliated to Soochow University,Changzhou second hospital affiliated to Nanjing Medical University and Changzhou hospital affiliated to Nanjing University of Traditional Chinese Medicine from January 2014 to July 2014.93 patients with IBD were enrolled into the study.The written consent form was signed and the case data of patients was gathered within 24 hours after hospitalization.On the basis of reviewing literature,consulting two digestive experts and one nursing expert,formulated a collection list of the cases data.The content of the list included patient’s general information, nutrition indexes and disease information.The general information included bed number, name, age, gender, admission number,diagnosis and admission time;Nutrition indexes included body measurement indexes(height,weight,abdomen circumference,arm muscle circumference,triceps skin-fold thickness, loss weight for past three months),laboratory examination indexes within 48 hours after admission(albumin, prealbumin, hemoglobin and total lymphocyte count),and disease information(course of disease and disease severity),assessed the patients’ nutritional status with MUST and NRS2002.Results:1.The Spearman correlation check of MUST and NRS2002 rs=0.846,and P<0.001,the two tools had good correlation,Kappa consistency check k=0.876,P<0.001,the two tools had higher consistency;And the two methods also had some consistency in terms of age,gender,diagnosis,course of disease and disease severity;The incidence of the screening result of MUST was 69.9%(65/93),and the incidence of the screening result of NRS2002 was 66.7%(62/93),the screening result of MUST was higher than that of NRS2002,but there were no significant differences.2.According to the result of NRS2002 and MUST,various traditional nutrition indicators of no nutritional risk group were higher than those of having nutritional risk group,there were significant differences between the two groups;But TLC is similar.3.According to the result of NRS2002 and MUST,the hospitalization duration and medical expenses of having nutritional risk group were higher than those of no nutritional risk group,there were significant differences between the two groups.4.If we regarded the nutritional risk of hospitalized patients with IBD as the dependent variable,other variables which might be associated with nutritional risk as independent variables,took a binary logistic regression analysis,the results showed:Gender, diagnosis and disease severity were the independent risk factors of the nutritional risk of hospitalized patients with IBD,women’s nutritional risk was higher than men;CD’s nutritional risk was higher than UC;the more serious the disease, the higher incidence of nutritional risk;but had nothing to do with age and course of disease.Conclusions:1.The screening results of MUST and NRS2002 had good correlation and higher consistency;2.Traditional nutrition indicators were relatively sensitive indicators used in nutrition risk screening of hospitalized patients of IBD;But the immune function was similar;3.Nutritional risk can predict clinical outcomes;4.Gender, diagnosis and disease severity were the independent risk factors of the nutritional risk of hospitalized patients with IBD,women’s nutritional risk was higher than men;CD’s nutritional risk was higher than UC;the more serious the disease, the higher incidence of nutritional risk;but had nothing to do with age and course of disease.