Clinical Reserch On Treatment Of Percutaneous Acupoint Drug Delivery On Sepsis Patients With Gastrointestinal Dysfunction

ObjectiveThe study was observe the clinical curative effect of HuoXue Tiao-Chang Stick and XingQi TiaoChang Stick Sticking Shen Que(CV-8) in sepsis with gastrointestinal Dysfunction. Evaluate the effectiveness of point ap-plication in improving gastrointestinal function for sepsis. Explore the effectiveness and the effective drug of treating sepsis by acupoint stick-ing therapy improving gastrointestinal dysfunction.MethodsMake HuoXue TiaoChang stick,XingQi TiaoChang stick and placebo stick. Ninety patients with sepsis has gastrointestinal dysfunction were random-ly divided into HX group, XQ group and control group. In XQ group, patients was given XingQi TiaoChang stick at Shen Que(CV-8) based on conventional western medicine treatment. In the HX group, patients was given HuoXue TiaoChang stick at Shen Que(CV-8) based on conventional western medicine treatment. In the control group, patients was given the patch of placebo Sticking Shen Que(CV-8) based on conventional western medicine treatment. Recorded the inflammatory function, bowel sounds, the abdominal pressure, the gastric retention, the abdomen circumference, dysfunction score, the TCM symptom score of Gastrointestinal disease, in patients with ICU hospi-talization, SIRS score, MODS score, SOFA score and APACHE II score,28-day case fatality.The data would be analyzed by SPSS 18.0.ResultsThe times of bowel sounds of three groups increase after treatment. There was a significicant difference among the times of bowel sounds of three groups. There was a significicant difference in the times of bowel sounds between the HX group and the XQ group.There was a significicant difference among the abdominal pressure, the gastric retention, the abdomen circumference, dysfunction score, the inflammatory function, LAC, SIRS score, MODS score, SOFA score and APACHE Ⅱ score before and-after treatment.Compared to control group, there was a significicant difference among 28-day case fatality, the abdominal pressure, dysfunction score, the TCM symptom score of Gastrointestinal disease, NEUT%, PCT, LAC, MODS score, SOFA score and APACHE II score in HX group and XQ group.There was a significicant difference among the abdominal pressure, the abdomen circumference, the TCM symptom score of Gastrointestinal di-sease, WBC, NEUT%, LAC, MODS score, SOFA score between HX group and XQ group.ConclusionHuoXue TiaoChang stick and XingQi TiaoChang stick can achieve to im-prove the treatment of bowel dysfunction in patients with sepsis by acu-point sticking therapy.HuoXue TiaoChang stick, XingQi TiaoChang stick can improve intestinal dysfunction in patients with sepsis severity and in-flammation, reduce 28-day case fatality and improve prognosis. After treat-ment, the bowel sounds, the abdominal pressure, dysfunction score, the TCM symptom score of Gastrointestinal disease of HX group and XQ group have significantly improved, and positively correlated with the degree of improvement in the condition was, suggesting that transcutaneous to drug treatment of sepsis can be achieved by improving the intestinal dysfunc-tion in patients with sepsis effect, indicating Evodia, Magnolia, Chuan-xiong were the effective drugs, and promoting blood circulation of qi and blood transfer method in accordance with the patch of promoting blood Circulation to adjust intestinal function composition may be more effect-tive.