The Study On The Correlation Between TCM SYN Drome Of Type 2 Diabetes Mellitus With Dyslipi Demia And The Indexs Of Coronary Heart Diseas E Risk Factors,Like HCY, ASP, Adiponectin And So On

Objective: Provide objective reference index for TCM syndrome differentiation of diabetic dyslipidemia types, explore the relationship between TCM syndrome type of type 2 diabetes with dyslipidemia and coronary heart disease, study the evolution of TCM syndrome types of abnormal blood lipid in type 2 diabetes mellitus.Method: On the basis of traditional Chinese medicine and Western medicine diagnostic criteria andexclusion criteria, selected 30 patients abnormal blood lipid in type 2diabetes phlegm obstruction, deficiency of both qi and Yin, Spleen kidney yang deficiency, Liver kidney yin deficiency type, Blood stasis, there were 15 male cases and15 female cases.Detect The plasma lipids, blood glucose, plasma homocysteine(Hcy), adiponectin(ADPN), acylation stimulating protein(ASP) and other indicators, analyse the relationship between blood lipid in type 2 diabetes anomaly in differentsyndrome type and the above indexes.Result::1.In syndrome types of diabetic dyslipidemia, BMI, cholesterol, triglyceride, low density lipoprotein cholesterol level was higher, high-density lipoprotein was lower in Phlegm obstruction, differences were statistically significance compared with other various syndromes of group.(P<0.05 or P<0.01)2.Courses of disease in Blood stasis and Yang deficiency of spleen and kidney were longer than Liver kidney yin deficiency type, Deficiency of both qi and Yin,Phlegm obstruction type, differences were statistically significance.(P<0.05 or P<0.01)The levels of Hb Alc and FPG in Spleen kidney yang deficiency and Blood stasis were higher than Liver kidney yin deficiency type, Deficiency of both qi and Yin and Phlegm obstruction type, differences were statistically significance.(P<0.05 or P<0.01)However, differences were not statistically significance in FINS levels between the Various types. Insulin resistance index was higher in Blood stasis, differences werestatistically significance compared with other various syndromes of group.(P<0.05 or P<0.01)3.In the syndrome types of type 2 diabetic dyslipidemia,Hcy of Blood stasis was higher and ADPN was lower. Differences were statistically significance compared with other various syndromes of group.(P<0.05 or P<0.01) ASP of Blood stasis and Phlegm obstruction type was higher, differences were statistically significance compared with other various syndromes of group.(P<0.05 or P<0.01)Conclusion:1. There are some differences in the syndromes of Type 2 diabetic dyslipidemia on the level of TG, TC, LDL-C, HDL-C, BMI, FPG, glycosylated hemoglobin, IR, Hcy, ASP,APN. The above index can be regarded as the objective reference index of the disease dialectical typing.2. Patient’s control in blood lipid and weight is poor, which increased risk of coronary heart disease. Phlegm is the pathological factors that can cause dyslipidemia and obesity.The use of jianpihuashi can improve patients with dyslipidemia and obesity status.3. Dyslipidemia in type 2 diabetic patients with abnormal blood stasis can cause a higher risk of coronary heart disease. Screening of blood stasis in patients with coronary heart disease should be paid more attention to in case of early diagnosis, prevention and treatment. Promoting blood circulation and removing blood stasis is an important treatment method to prevent and cure coronary heart disease.4. This disease is likeiy to develop into Yang deficiency and blood stasis. Promoting blood circulation and removing blood stasis can exists in treatment of this disease From the beginning to the end. Warming-yang should be paid more attention to as well.