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Characteristics Of TCM Syndromes In 125 Patients With Coronary Heart Disease Complicated With Hypertension And Dyslipidemia Confirmed By Coronary Angiography

Posted on:2022-04-22Degree:MasterType:Thesis
Country:ChinaCandidate:X Y GuFull Text:PDF
GTID:2504306317470014Subject:Traditional Chinese Medicine
Abstract/Summary:PDF Full Text Request
Objective:To analyze the distribution of general data of patients with angina pectoris of coronary heart disease complicated with hypertension and dyslipidemia,the distribution of general data among different syndromes,the distribution characteristics of TCM syndromes and the correlation between TCM syndromes and coronary angiography results.Methods:From January 2019 to January 2020,125 patients who met the diagnostic criteria of angina pectoris of coronary heart disease complicated with hypertension and dyslipidemia and did not meet the exclusion criteria were selected from the Department of cardiovascular medicine of Wuhan integrated traditional Chinese and Western medicine hospital.The basic information,four diagnostic data,examination results and coronary angiography results of patients were collected.Four diagnostic information was used to judge the syndrome type of patients,and the general information and coronary angiography results were statistically analyzed to explore the distribution characteristics of TCM syndrome and its relationship with coronary angiography results.Results:1.General data:(1)age: the minimum age was 35 years old,the maximum age was 79 years old,and the median age was 63 years old.(2)Gender: male 69 cases,female 56 cases,male to female ratio was 1.23:1.(3)History of smoking and drinking: 60 cases had a history of smoking,accounting for 48%;37 cases had a history of drinking,accounting for 29.6%.(4)Complications: 102 cases with carotid plaque,accounting for 81.6%;71 cases with cerebral infarction,accounting for 56.8%;58 cases with hyperuricemia,accounting for 46.4%;51 cases with hyperglycemia,accounting for40.8%.(5)Clinical classification of dyslipidemia: 36 cases of hypercholesterolemia,accounting for 28.8%;32 cases of high TG,accounting for 25.6%;52 cases of mixed hyperlipidemia,accounting for 41.6%;5 cases of simple low HDL-C,accounting for 4%.(6)Hypertension classification: 18 cases of grade 1 hypertension,accounting for 14.4%;27 cases of grade 2 hypertension,accounting for 21.6%;80 cases of grade 3 hypertension,accounting for 64%.(7)The number of coronary artery lesions: single branch 65 cases,accounting for 52%;double branch 26 cases,accounting for 20.8%;multi branch 34 cases,accounting for 27.2%.(8)Classification of coronary artery lesions: 53 cases were grade II,accounting for42.4%;72 cases were grade III,accounting for 57.6%.2.Distribution of TCM syndrome types: 43 cases of phlegm turbidity blocking syndrome,accounting for 34.4%;30 cases of qi deficiency and blood stasis syndrome,accounting for 24%;24 cases of qi stagnation and blood stasis syndrome,accounting for 19.2%;16 cases of Qi Yin deficiency syndrome,accounting for 12.8%;12cases of Yang deficiency and cold coagulation syndrome,accounting for 9.6%.3.Data analysis among syndrome types:(1)gender: there was no statistical significance difference in the distribution of gender among the five groups(P > 0.05).(2)Age: there was no statistical significance difference in the distribution of different age groups among the five groups(P > 0.05).(3)History of smoking and drinking: there was statistical significance difference in the distribution of smoking history among the five groups(P < 0.05),and there was statistical significance difference between phlegm turbid stagnation syndrome and yang deficiency cold coagulation syndrome and qi stagnation and blood stasis syndrome(P < 0.05),but there was no statistical significance difference between the other groups;there was statistical significance difference in the distribution of drinking history among the five groups(P < 0.05),and there was statistical significance difference between phlegm turbid stagnation syndrome and yang deficiency cold coagulation syndrome and qi stagnation and blood stasis syndrome(P < 0.05),and there was no statistical significance difference between the other groups.(4)Complications: the difference of hyperglycemia,carotid plaque,hyperuricemia,cerebral infarction in the five groups were not statistically significant(P > 0.05).(5)Clinical classification of hyperlipidemia: the difference of the distribution of clinical classification of hyperlipidemia among the five groups was statistically significant(P < 0.05),in which the deficiency of both qi and Yin,qi stagnation and blood stasis syndrome were compared with phlegm stagnation syndrome,and the difference between Qi stagnation and blood stasis syndrome and Qi deficiency and blood stasis syndrome was statistically significant(P < 0.05),but there was no statistical significance difference between the other groups.(6)Hypertension classification: there was no statistical significance difference in the distribution of hypertension classification among the five groups(P > 0.05).(7)The number of coronary artery lesions: the difference of the distribution of coronary artery lesions in the five groups was statistically significant(P < 0.05),and the difference between Qi stagnation and blood stasis syndrome and Qi deficiency and blood stasis syndrome,phlegm turbidity obstruction syndrome was statistically significant(P < 0.05),but there was no significant difference between the other groups.(8)Gensini score of coronary artery disease: the difference of Gensini score of five groups was statistically significant(P < 0.05),and the difference between Qi and yin deficiency syndrome and the other four groups was statistically significant(P < 0.05).Conclusion:1.Angina pectoris patients with hypertension and dyslipidemia are mainly middle-aged and elderly people,more men than women,often combined with smoking and drinking history,the main complications are carotid plaque and cerebral infarction,the clinical classification of dyslipidemia is mainly mixed hyperlipidemia,the hypertension classification is mainly grade3,the number of coronary artery lesions is single,the classification is mainly grade III(severe stenosis),The degree of stenosis was severe.2.The syndrome differentiation of angina pectoris patients with hypertension and dyslipidemia is phlegm turbidity blocking syndrome,Qi deficiency and blood stasis syndrome,qi stagnation and blood stasis syndrome,Qi and yin deficiency syndrome and yang deficiency and cold coagulation syndrome,most of which are phlegm turbidity blocking syndrome and Qi deficiency and blood stasis syndrome.3.The TCM syndrome types of angina pectoris patients with hypertension and dyslipidemia are related to drinking history,smoking history,clinical classification of dyslipidemia,number of coronary artery lesions and Gensini score of coronary artery:the patients with smoking history and drinking history are less likely to be identified as qi stagnation and blood stasis syndrome,while the clinical classification of dyslipidemia in patients with phlegm turbidity syndrome and Qi deficiency and blood stasis syndrome is mainly mixed hyperlipidemia,The patients with qi stagnation and blood stasis syndrome had single coronary artery lesion,while the Gensini score of patients with Qi Yin deficiency syndrome was low.4.The TCM syndrome types of patients with angina pectoris,hypertension and dyslipidemia have no clear relationship with gender,age,complications,hypertension classification and other factors.
Keywords/Search Tags:Coronary heart disease, Angina pectoris, Hypertension, Dyslipidemia, TCM syndrome type, Coronary angiography results
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