Study On The Correlation Between Cardiovascular Disease Risk Assessment And Traditional Chinese Medical Constitution

ObjectivesThis study collected clinical data of asymptomatic physical examination population, took cardiovascular disease risk assessment to find out intermediate or high risk cases, and explored their constitutions of traditional Chinese medicine and correlation between cardiovascular risk assessment and TCM constitution. Thus, with the help of modern disease predicting tools, a mothed to assess cardiovascular disease risk by identifying constitutions of TCM would be put forward, and a theoretical basis would be provided for preventing cardiovascular disease by adjusting constitution.MethodsIn this study, gender, age, body mass index, systolic blood pressure, total cholesterol, smoking history, diabetes history and TCM constitution of 752 physical examination population, aged 35 to 75 years and without clinical symptoms, were collected. The assessment tool introduced in "The Chinese experts’consensus on asymptomatic adult cardiovascular disease risk assessment" was used to predict the absolute risk of ischemic cardiovascular disease for 10 years. All cases were divided into two groups:low-risk group (LR group)(absolute risk<10%) and intermediate or high-risk group (IHR group) (absolute risk≥10%). Compared with average risk of the same age group, a reasonably high-risk group(RHR group) was screened. Statistical software was used to analyze the TCM Constitutions of IHR group and RHR group, and explore the correlation between cardiovascular disease risk assessment and TCM constitution.ResultsThere were 710 cases (94.41%) in LR group and 42 cases (5.59%) in IHR group, while 319 cases (42.42%) were with simplex constitution, and 433 cases (60.99%) were with composite constitution. The top three constitutions of IHR group were Qi-deficient and Phlegm-dampness constitution (26.19%), Phlegm-dampness constitution(21.43%), Qi-deficient and Stagnant Blood constitution (11.90%), and the odds of Qi-deficient and Phlegm-dampness constitution in IHR group was significantly higher than LR group (P<0.05). When those composite constitutions were divided into simplex ones, the top three constitutions came out to be Qi-deficient constitution (34.67%), Phlegm-dampness constitution (36.00%), and Stagnant Blood constitution (14.67%), while the odds of Phlegm-dampness constitution was significantly higher than LR group (P<0.05). In 657 cases aged 35 to 59, there were 237 cases (36.07%) in RHR group, which had Phlegm-dampness constitution (19.83%), Qi-deficient and Phlegm-dampness constitution (13.08%), and Qi-deficient and Stagnant Blood constitution (11.39%) as the top three, and with those composite constitutions divided, they got Qi-deficient constitution (26.13%), Phlegm-dampness constitution (26.38%) and Stagnant Blood constitution (16.33%). Compared with reasonably low-risk group (RLR group), the odds of Phlegm-dampness constitution and Stagnant Blood constitution were significantly higher than RLR group (P<0.05). Logistic regression analyze of correlation between cardiovascular disease risk assessment and TCM constitutions showed that in the test level of P<0.05, Qi-deficient constitution, Phlegm-dampness constitution and Stagnant Blood constitution were included in the model of logistic regression, with ORs of 95%CI>1 and regression coefficients>0.ConclusionQi-deficient constitution, Phlegm-dampness constitution and Stagnant Blood constitution more likely be found in high cardiovascular-risk population than other TCM constitutions, and the combinations of these three constitutions may also mean higher cardiovascular risk. Qi-deficient constitution, Phlegm-dampness constitution and Stagnant Blood constitution can be recognized as high risk factors of cardiovascular disease.